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Literature DB >> 12359740

Analysis and function of transcriptional regulatory elements: insights from Drosophila.

Abstract

Analysis of gene expression is assuming an increasingly important role in elucidating the molecular basis of insect biology. Transcriptional regulation of gene expression is directed by a variety of cis-acting DNA elements that control spatial and temporal patterns of expression. This review summarizes current knowledge about properties of transcriptional regulatory elements, based largely on research in Drosophila melanogaster, and outlines ways that new technologies are providing tools to facilitate the study of transcriptional regulatory elements in other insects.

Entities: Species

Mesh：

Substances：
DNA

Year: 2001 PMID： 12359740 DOI： 10.1146/annurev.ento.48.091801.112749

Source DB: PubMed Journal: Annu Rev Entomol ISSN： 0066-4170 Impact factor: 19.686

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Cited

35 in total

1. Distance preferences in the arrangement of binding motifs and hierarchical levels in organization of transcription regulatory information.

Authors: Vsevolod J Makeev; Alexander P Lifanov; Anna G Nazina; Dmitri A Papatsenko
Journal: Nucleic Acids Res Date: 2003-10-15 Impact factor: 16.971

2. Transgene-mediated suppression of dengue viruses in the salivary glands of the yellow fever mosquito, Aedes aegypti.

Authors: G Mathur; I Sanchez-Vargas; D Alvarez; K E Olson; O Marinotti; A A James
Journal: Insect Mol Biol Date: 2010-12 Impact factor: 3.585

3. Quantitative analysis of binding motifs mediating diverse spatial readouts of the Dorsal gradient in the Drosophila embryo.

Authors: Dmitri Papatsenko; Michael Levine
Journal: Proc Natl Acad Sci U S A Date: 2005-03-28 Impact factor: 11.205

Analysis and function of transcriptional regulatory elements: insights from Drosophila.

1. Distance preferences in the arrangement of binding motifs and hierarchical levels in organization of transcription regulatory information.

2. Transgene-mediated suppression of dengue viruses in the salivary glands of the yellow fever mosquito, Aedes aegypti.

3. Quantitative analysis of binding motifs mediating diverse spatial readouts of the Dorsal gradient in the Drosophila embryo.

Review 4. Identifying regulatory elements in eukaryotic genomes.

5. Quantitative modeling of a gene's expression from its intergenic sequence.

6. Combinatorial activation and concentration-dependent repression of the Drosophila even skipped stripe 3+7 enhancer.

7. Regulation of Ubx expression by epigenetic enhancer silencing in response to Ubx levels and genetic variation.

8. Genomic characterization of a repetitive motif strongly associated with developmental genes in Drosophila.

9. Core promoter sequences contribute to ovo-B regulation in the Drosophila melanogaster germline.

10. Evolution of regulatory sequences in 12 Drosophila species.