Literature DB >> 12298051

NMR reporter screening for the detection of high-affinity ligands.

Wolfgang Jahnke1, Philipp Floersheim, Christian Ostermeier, Xiaolu Zhang, Rene Hemmig, Konstanze Hurth, Doncho P Uzunov.   

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Year:  2002        PMID: 12298051     DOI: 10.1002/1521-3773(20020916)41:18<3420::AID-ANIE3420>3.0.CO;2-E

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  13 in total

1.  Enhanced signal dispersion in saturation transfer difference experiments by conversion to a 1D-STD-homodecoupled spectrum.

Authors:  Manuel Martín-Pastor; Marino Vega-Vázquez; Antonia De Capua; Angeles Canales; Sabine André; Hans-Joachim Gabius; Jesús Jiménez-Barbero
Journal:  J Biomol NMR       Date:  2006-09-20       Impact factor: 2.835

2.  Development of molecular probes for second-site screening and design of protein tyrosine phosphatase inhibitors.

Authors:  Jesus Vazquez; Lutz Tautz; Jennifer J Ryan; Kristiina Vuori; Tomas Mustelin; Maurizio Pellecchia
Journal:  J Med Chem       Date:  2007-03-30       Impact factor: 7.446

3.  Development of paramagnetic probes for molecular recognition studies in protein kinases.

Authors:  Jesus Vazquez; Surya K De; Li-Hsing Chen; Megan Riel-Mehan; Aras Emdadi; Jason Cellitti; John L Stebbins; Michele F Rega; Maurizio Pellecchia
Journal:  J Med Chem       Date:  2008-06-26       Impact factor: 7.446

Review 4.  Cryo-EM in drug discovery: achievements, limitations and prospects.

Authors:  Jean-Paul Renaud; Ashwin Chari; Claudio Ciferri; Wen-Ti Liu; Hervé-William Rémigy; Holger Stark; Christian Wiesmann
Journal:  Nat Rev Drug Discov       Date:  2018-06-08       Impact factor: 84.694

5.  Affinity screening using competitive binding with fluorine-19 hyperpolarized ligands.

Authors:  Yaewon Kim; Christian Hilty
Journal:  Angew Chem Int Ed Engl       Date:  2015-02-20       Impact factor: 15.336

6.  Parallelized Ligand Screening Using Dissolution Dynamic Nuclear Polarization.

Authors:  Yaewon Kim; Mengxiao Liu; Christian Hilty
Journal:  Anal Chem       Date:  2016-10-25       Impact factor: 6.986

7.  Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery.

Authors:  Wolfgang Jahnke; Jean-Michel Rondeau; Simona Cotesta; Andreas Marzinzik; Xavier Pellé; Martin Geiser; André Strauss; Marjo Götte; Francis Bitsch; René Hemmig; Chrystèle Henry; Sylvie Lehmann; J Fraser Glickman; Thomas P Roddy; Steven J Stout; Jonathan R Green
Journal:  Nat Chem Biol       Date:  2010-08-15       Impact factor: 15.040

8.  Estimating protein-ligand binding affinity using high-throughput screening by NMR.

Authors:  Matthew D Shortridge; David S Hage; Gerard S Harbison; Robert Powers
Journal:  J Comb Chem       Date:  2008-10-03

9.  Reporter ligand NMR screening method for 2-oxoglutarate oxygenase inhibitors.

Authors:  Ivanhoe K H Leung; Marina Demetriades; Adam P Hardy; Clarisse Lejeune; Tristan J Smart; Andrea Szöllössi; Akane Kawamura; Christopher J Schofield; Timothy D W Claridge
Journal:  J Med Chem       Date:  2013-01-04       Impact factor: 7.446

10.  Differential Epitope Mapping by STD NMR Spectroscopy To Reveal the Nature of Protein-Ligand Contacts.

Authors:  Serena Monaco; Louise E Tailford; Nathalie Juge; Jesus Angulo
Journal:  Angew Chem Int Ed Engl       Date:  2017-10-23       Impact factor: 15.336

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