Literature DB >> 12270966

Vagus nerve stimulation therapy, epilepsy, and device parameters: scientific basis and recommendations for use.

Christi Heck1, Sandra L Helmers, Christopher M DeGiorgio.   

Abstract

Our understanding of a precise dose-response relationship for vagus nerve stimulation (VNS) therapy in the treatment of seizures is still evolving. Because several parameters are involved in VNS therapy, the individual contribution of each is not well understood. This review discusses the efficacy of stimulation parameters used in the VNS clinical trials. The background, influence on safety and efficacy, and role in helping to achieve seizure control are discussed for each VNS device parameter: output current, pulse duration, frequency, and duty cycle. Finally, we provide an algorithm for the adjustment of VNS device settings (see Appendices).

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Year:  2002        PMID： 12270966     DOI： 10.1212/wnl.59.6_suppl_4.s31

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  32 in total

1.  Electrical stimulation in epilepsy: vagus nerve and brain stimulation.

Authors:  Barbara C Jobst
Journal:  Curr Treat Options Neurol       Date:  2010-09       Impact factor: 3.598

Review 2.  Neurostimulation for drug-resistant epilepsy.

Authors:  Christopher M DeGiorgio; Scott E Krahl
Journal:  Continuum (Minneap Minn)       Date:  2013-06

3.  Vagus Nerve Stimulation Applied with a Rapid Cycle Has More Profound Influence on Hippocampal Electrophysiology Than a Standard Cycle.

Authors:  Lars E Larsen; Wytse J Wadman; Daniele Marinazzo; Pieter van Mierlo; Jean Delbeke; Sofie Daelemans; Mathieu Sprengers; Lisa Thyrion; Wouter Van Lysebettens; Evelien Carrette; Paul Boon; Kristl Vonck; Robrecht Raedt
Journal:  Neurotherapeutics       Date:  2016-07       Impact factor: 7.620

4.  Vagus Nerve Stimulation: Rapid versus Slow Cycling in a Laboratory Model.

Authors:  Robert S Fisher
Journal:  Neurotherapeutics       Date:  2016-07       Impact factor: 7.620

5.  Parametric characterization of neural activity in the locus coeruleus in response to vagus nerve stimulation.

Authors:  Daniel R Hulsey; Jonathan R Riley; Kristofer W Loerwald; Robert L Rennaker; Michael P Kilgard; Seth A Hays
Journal:  Exp Neurol       Date:  2016-12-14       Impact factor: 5.330

6.  Long-term results of vagus nerve stimulation in children and adolescents with drug-resistant epilepsy.

Authors:  Beata Majkowska-Zwolińska; Piotr Zwoliński; Marcin Roszkowski; Krzysztof Drabik
Journal:  Childs Nerv Syst       Date:  2012-01-06       Impact factor: 1.475

Review 7.  Vagus nerve stimulation for epilepsy and depression.

Authors:  Andrew H Milby; Casey H Halpern; Gordon H Baltuch
Journal:  Neurotherapeutics       Date:  2008-01       Impact factor: 7.620

8.  Effect of vagus nerve stimulation in post-traumatic epilepsy and failed epilepsy surgery : preliminary report.

Authors:  Hai-Ong Lee; Eun-Jeong Koh; Young-Min Oh; Seung-Soo Park; Ki-Hun Kwon; Ha-Young Choi
Journal:  J Korean Neurosurg Soc       Date:  2008-10-30

9.  Vagal nerve stimulation for drug-resistant epilepsies in different age, aetiology and duration.

Authors:  Gabriella Colicchio; Domenico Policicchio; Giulia Barbati; Elisabetta Cesaroni; Filomena Fuggetta; Mario Meglio; Fabio Papacci; Franco Rychlicki; Massimo Scerrati; Nelia Zamponi
Journal:  Childs Nerv Syst       Date:  2010-01-21       Impact factor: 1.475

10.  Neuromodulation in the Treatment of Epilepsy.

Authors:  George Nune; Christopher DeGiorgio; Christianne Heck
Journal:  Curr Treat Options Neurol       Date:  2015-10       Impact factor: 3.598
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