Literature DB >> 12213658

Transcript elongation on a nucleoprotein template.

Grant A Hartzog1, Jennifer L Speer, Derek L Lindstrom.   

Abstract

Chromatin forms a general, repeating barrier to elongation of transcripts by eukaryotic RNA polymerases. Recent studies of nucleosome structure and histone modifications reveal a set of likely mechanisms for control of elongation through chromatin. Genetic and biochemical studies of transcription have identified a set of accessory factors for transcript elongation by RNA polymerase II (Pol II) that appear to function in the context of chromatin. The C-terminal repeated domain (CTD) of Pol II may also play a role in regulating elongation through chromatin.

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Year:  2002        PMID： 12213658     DOI： 10.1016/s0167-4781(02)00458-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  26 in total

1.  The topoisomerase IIbeta circular clamp arrests transcription and signals a 26S proteasome pathway.

Authors:  Hai Xiao; Yong Mao; Shyamal D Desai; Nai Zhou; Chun-Yuan Ting; Jaulang Hwang; Leroy F Liu
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-10       Impact factor: 11.205

Review 2.  Eukaryotic MCM proteins: beyond replication initiation.

Authors:  Susan L Forsburg
Journal:  Microbiol Mol Biol Rev       Date:  2004-03       Impact factor: 11.056

3.  An E3 ubiquitin ligase prevents ectopic localization of the centromeric histone H3 variant via the centromere targeting domain.

Authors:  Prerana Ranjitkar; Maximilian O Press; Xianhua Yi; Richard Baker; Michael J MacCoss; Sue Biggins
Journal:  Mol Cell       Date:  2010-11-12       Impact factor: 17.970

4.  A gene-specific requirement for FACT during transcription is related to the chromatin organization of the transcribed region.

Authors:  Silvia Jimeno-González; Fernando Gómez-Herreros; Paula M Alepuz; Sebastián Chávez
Journal:  Mol Cell Biol       Date:  2006-09-25       Impact factor: 4.272

Review 5.  Transcription through chromatin by RNA polymerase II: histone displacement and exchange.

Authors:  Olga I Kulaeva; Daria A Gaykalova; Vasily M Studitsky
Journal:  Mutat Res       Date:  2007-01-21       Impact factor: 2.433

6.  Uncoupling of the patterns of chromatin association of different transcription elongation factors by a histone H3 mutant in Saccharomyces cerevisiae.

Authors:  Amanda Lloyd; Katie Pratt; Erica Siebrasse; Matthew D Moran; Andrea A Duina
Journal:  Eukaryot Cell       Date:  2008-12-01

7.  An evolutionarily 'young' lysine residue in histone H3 attenuates transcriptional output in Saccharomyces cerevisiae.

Authors:  Edel M Hyland; Henrik Molina; Kunal Poorey; Chunfa Jie; Zhi Xie; Junbiao Dai; Jiang Qian; Stefan Bekiranov; David T Auble; Akhilesh Pandey; Jef D Boeke
Journal:  Genes Dev       Date:  2011-06-15       Impact factor: 11.361

8.  The growing pre-mRNA recruits actin and chromatin-modifying factors to transcriptionally active genes.

Authors:  Mikael Sjölinder; Petra Björk; Emilia Söderberg; Nafiseh Sabri; Ann-Kristin Ostlund Farrants; Neus Visa
Journal:  Genes Dev       Date:  2005-08-15       Impact factor: 11.361

9.  The Ras/PKA signaling pathway may control RNA polymerase II elongation via the Spt4p/Spt5p complex in Saccharomyces cerevisiae.

Authors:  Susie C Howard; Arelis Hester; Paul K Herman
Journal:  Genetics       Date:  2003-11       Impact factor: 4.562

10.  Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif.

Authors:  Angela Hirtreiter; Gerke E Damsma; Alan C M Cheung; Daniel Klose; Dina Grohmann; Erika Vojnic; Andrew C R Martin; Patrick Cramer; Finn Werner
Journal:  Nucleic Acids Res       Date:  2010-03-02       Impact factor: 16.971
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