Literature DB >> 12209429

The influences of biomechanical factors on cartilage regeneration after high tibial osteotomy for knees with medial compartment osteoarthritis: clinical and arthroscopic observations.

Takeshi Kanamiya1, Masatoshi Naito, Michiya Hara, Ichiro Yoshimura.   

Abstract

PURPOSE: A high tibial osteotomy (HTO) is often performed on knees with medial compartment osteoarthritis. However, in varus knees with medial compartment osteoarthritis, degeneration of the articular cartilage tends to progress due to medial deviation of the mechanical axis. This can result in eburnated bone. A widening of the medial joint space has been observed after HTO with a proper correction as a result of decreased stress on the load-bearing cartilage in the medial compartment. Researchers have reported obtaining a repair of the articular cartilage with both eburnation and clinical improvement using HTO in patients showing a medial deviation of the mechanical axis. However, which factors influence cartilage regeneration remain unclear. The purpose of this study was to quantitatively evaluate the influence of cartilage regeneration after a high tibial osteotomy for knees with medial compartment osteoarthritis. TYPE OF STUDY: Observational cohort study.
METHODS: The study involved 58 knees in 47 patients. A modified Noyes classification was used for arthroscopic grading. The patients underwent a second look arthroscopic evaluation of the articular cartilage 18 months after surgery. The articular cartilage was classified as no regenerative change (grade 1), white scattering with fibrocartilage (grade 2), partial coverage with fibrocartilage (grade 3), and even coverage with fibrocartilage (grade 4). The functional results were evaluated according to the Japanese Orthopedic Association score for osteoarthritic knees (JOA score), femorotibial angle (FTA), percentage of mechanical axis, and body mass index (BMI).
RESULTS: Partial or even coverage with fibrocartilage (grade 3 and 4) was achieved on 55% of the femorotibial joint surfaces. A repair with white scattering with fibrocartilage (grade 2) was achieved in 34%, and 3 knees showed no regenerative change (grade 1). At follow up, significant differences were seen between grade 4 and grade 1 in JOA score and percentage of mechanical axis.
CONCLUSIONS: This study demonstrates the correlation between the visible improvement of the articular surface, the functional score, and the degree of correction obtained with a lateral closing wedge HTO.

Entities:  

Mesh:

Year:  2002        PMID: 12209429     DOI: 10.1053/jars.2002.35258

Source DB:  PubMed          Journal:  Arthroscopy        ISSN: 0749-8063            Impact factor:   4.772


  29 in total

Review 1.  Surgical treatment for early osteoarthritis. Part II: allografts and concurrent procedures.

Authors:  A H Gomoll; G Filardo; F K Almqvist; W D Bugbee; M Jelic; J C Monllau; G Puddu; W G Rodkey; P Verdonk; R Verdonk; S Zaffagnini; M Marcacci
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-11-09       Impact factor: 4.342

2.  Tibial slope and high tibial osteotomy using the circular external fixator.

Authors:  Taner Gunes; Cengiz Sen; Mehmet Erdem
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2006-08-09       Impact factor: 4.342

3.  Allogeneic umbilical cord blood-derived mesenchymal stem cells combined with high tibial osteotomy: a retrospective study on safety and early results.

Authors:  Young-Woo Chung; Hong-Yeol Yang; Sung-Ju Kang; Eun-Kyoo Song; Jong-Keun Seon
Journal:  Int Orthop       Date:  2020-10-17       Impact factor: 3.075

Review 4.  Cartilage repair and joint preservation: medical and surgical treatment options.

Authors:  Henning Madry; Ulrich Wolfgang Grün; Gunnar Knutsen
Journal:  Dtsch Arztebl Int       Date:  2011-10-07       Impact factor: 5.594

Review 5.  Load distribution in early osteoarthritis.

Authors:  Andreas H Gomoll; Peter Angele; Vincenzo Condello; Vincenzo Madonna; Henning Madry; Pietro Randelli; Nogah Shabshin; Peter Verdonk; Rene Verdonk
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-04-16       Impact factor: 4.342

6.  The Effect of Treatment with Resiniferatoxin and Capsaicin on Dynamic Weight Bearing Measures and Evoked Pain Responses in a Chronic Inflammatory Arthritis Murine Model.

Authors:  Joseph Bert; Maren L Mahowald; Sandra Frizelle; Christopher W Dorman; Sonia C Funkenbusch; Hollis E Krug
Journal:  Intern Med Rev (Wash D C)       Date:  2016

7.  Patellar morphology and femoral component geometry influence patellofemoral contact stress in total knee arthroplasty without patellar resurfacing.

Authors:  Atsushi Takahashi; Hirotaka Sano; Masahiro Ohnuma; Mitsuhiro Kashiwaba; Daisuke Chiba; Masayuki Kamimura; Takehiko Sugita; Eiji Itoi
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-11-16       Impact factor: 4.342

Review 8.  Management of Posttraumatic Ankle Arthritis: Literature Review.

Authors:  Samuel O Ewalefo; Malcolm Dombrowski; Takashi Hirase; Jorge L Rocha; Mitchell Weaver; Alex Kline; Dwayne Carney; MaCalus V Hogan
Journal:  Curr Rev Musculoskelet Med       Date:  2018-12

9.  Implantation of mesenchymal stem cells in combination with allogenic cartilage improves cartilage regeneration and clinical outcomes in patients with concomitant high tibial osteotomy.

Authors:  Yong Sang Kim; Pill Ku Chung; Dong Suk Suh; Dong Beom Heo; Dae Hyun Tak; Yong Gon Koh
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2019-09-23       Impact factor: 4.342

10.  Factors affecting cartilage repair after medial opening-wedge high tibial osteotomy.

Authors:  Ken Kumagai; Yasushi Akamatsu; Hideo Kobayashi; Yoshihiro Kusayama; Tomihisa Koshino; Tomoyuki Saito
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-03-31       Impact factor: 4.342

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.