Literature DB >> 12150821

RNA interference: the new somatic cell genetics?

Patrick J Paddison1, Gregory J Hannon.   

Abstract

RNAi is evolving into a powerful tool for manipulating gene expression in mammalian cells with potential utility for investigating gene function, for high-throughput, function-based genetic screens and potentially for development as a therapeutic tool.

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Year:  2002        PMID： 12150821     DOI： 10.1016/s1535-6108(02)00092-2

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  48 in total

1.  NPAT expression is regulated by E2F and is essential for cell cycle progression.

Authors:  Guang Gao; Adrian P Bracken; Karina Burkard; Diego Pasini; Marie Classon; Claire Attwooll; Masashi Sagara; Takashi Imai; Kristian Helin; Jiyong Zhao
Journal:  Mol Cell Biol       Date:  2003-04       Impact factor: 4.272

2.  A novel approach for evaluating the efficiency of siRNAs on protein levels in cultured cells.

Authors:  Weilin Wu; Emily Hodges; Jenny Redelius; Christer Höög
Journal:  Nucleic Acids Res       Date:  2004-01-22       Impact factor: 16.971

3.  Generation of single and double knockdowns in polarized epithelial cells by retrovirus-mediated RNA interference.

Authors:  Sebastian Schuck; Aki Manninen; Masanori Honsho; Joachim Füllekrug; Kai Simons
Journal:  Proc Natl Acad Sci U S A       Date:  2004-03-29       Impact factor: 11.205

Review 4.  Optimizing RNA interference for application in mammalian cells.

Authors:  René H Medema
Journal:  Biochem J       Date:  2004-06-15       Impact factor: 3.857

5.  Polypeptide modulators of caspase recruitment domain (CARD)-CARD-mediated protein-protein interactions.

Authors:  Yadira Palacios-Rodríguez; Guillermo García-Laínez; Mónica Sancho; Anna Gortat; Mar Orzáez; Enrique Pérez-Payá
Journal:  J Biol Chem       Date:  2011-11-07       Impact factor: 5.157

Review 6.  The contradictory definitions of heterochromatin: transcription and silencing.

Authors:  Kathryn L Huisinga; Brent Brower-Toland; Sarah C R Elgin
Journal:  Chromosoma       Date:  2006-02-28       Impact factor: 4.316

7.  Suppression of prion protein in livestock by RNA interference.

Authors:  Michael C Golding; Charles R Long; Michelle A Carmell; Gregory J Hannon; Mark E Westhusin
Journal:  Proc Natl Acad Sci U S A       Date:  2006-03-27       Impact factor: 11.205

Review 8.  RNAi in embryonic stem cells.

Authors:  Li Ding; Frank Buchholz
Journal:  Stem Cell Rev       Date:  2006       Impact factor: 5.739

9.  Neurabin/protein phosphatase-1 complex regulates dendritic spine morphogenesis and maturation.

Authors:  Ryan T Terry-Lorenzo; David W Roadcap; Takeshi Otsuka; Thomas A Blanpied; Pedro L Zamorano; Craig C Garner; Shirish Shenolikar; Michael D Ehlers
Journal:  Mol Biol Cell       Date:  2005-03-02       Impact factor: 4.138

10.  Lentivirus-delivered stable gene silencing by RNAi in primary cells.

Authors:  Sheila A Stewart; Derek M Dykxhoorn; Deborah Palliser; Hana Mizuno; Evan Y Yu; Dong Sung An; David M Sabatini; Irvin S Y Chen; William C Hahn; Phillip A Sharp; Robert A Weinberg; Carl D Novina
Journal:  RNA       Date:  2003-04       Impact factor: 4.942
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