PURPOSE: To determine whether there are sex-related differences in vertebral cross-sectional dimensions, in paraspinous muscle area, and in the amount of fat in the subcutaneous and visceral compartments of prepubertal boys and girls. MATERIALS AND METHODS: Subcutaneous fat, visceral fat, paraspinous musculature, and vertebral cross-sectional dimensions were studied in 31 pairs of prepubertal healthy white girls and boys 5-10 years of age, rigorously matched for age, height, and weight. Data were analyzed with the Student t test and multiple regression analysis. RESULTS: Sex had a differential effect on fat accumulation and musculoskeletal development. Compared with boys, girls had, on average, 28% greater total fat and 30% higher subcutaneous fat (P <.001 for both), but 10% less paraspinous musculature (P =.002) and 15% smaller vertebral cross-sectional dimensions (P <.001). In contrast, the sexes were monomorphic for visceral fat (P =.24). Stepwise regression analysis indicated that only 22% of the difference in vertebral cross-sectional area could be explained by sex-related differences in paraspinous musculature. CONCLUSION: Together, these data indicate that sex is an important determinant of the morphology in humans well before the beginning of puberty. Copyright RSNA, 2002
PURPOSE: To determine whether there are sex-related differences in vertebral cross-sectional dimensions, in paraspinous muscle area, and in the amount of fat in the subcutaneous and visceral compartments of prepubertal boys and girls. MATERIALS AND METHODS: Subcutaneous fat, visceral fat, paraspinous musculature, and vertebral cross-sectional dimensions were studied in 31 pairs of prepubertal healthy white girls and boys 5-10 years of age, rigorously matched for age, height, and weight. Data were analyzed with the Student t test and multiple regression analysis. RESULTS: Sex had a differential effect on fat accumulation and musculoskeletal development. Compared with boys, girls had, on average, 28% greater total fat and 30% higher subcutaneous fat (P <.001 for both), but 10% less paraspinous musculature (P =.002) and 15% smaller vertebral cross-sectional dimensions (P <.001). In contrast, the sexes were monomorphic for visceral fat (P =.24). Stepwise regression analysis indicated that only 22% of the difference in vertebral cross-sectional area could be explained by sex-related differences in paraspinous musculature. CONCLUSION: Together, these data indicate that sex is an important determinant of the morphology in humans well before the beginning of puberty. Copyright RSNA, 2002
Authors: Vicente Gilsanz; Michelle L Smith; Fariba Goodarzian; Mimi Kim; Tishya A L Wren; Houchun H Hu Journal: J Pediatr Date: 2011-11-01 Impact factor: 4.406
Authors: Vicente Gilsanz; James Chalfant; Ashley O Mo; David C Lee; Frederick J Dorey; Steven D Mittelman Journal: J Clin Endocrinol Metab Date: 2009-06-16 Impact factor: 5.958
Authors: Tishya A L Wren; David C Lee; Reiko Hara; Susan A Rethlefsen; Robert M Kay; Frederick J Dorey; Vicente Gilsanz Journal: J Pediatr Orthop Date: 2010 Oct-Nov Impact factor: 2.324
Authors: Skorn Ponrartana; Carissa L Fisher; Patricia C Aggabao; Thomas A Chavez; Alexander M Broom; Tishya A L Wren; David L Skaggs; Vicente Gilsanz Journal: Pediatr Radiol Date: 2016-05-16