Literature DB >> 12147646

NADPH oxidase(s): new source(s) of reactive oxygen species in the vascular system?

L Van Heerebeek1, C Meischl, W Stooker, C J L M Meijer, H W M Niessen, D Roos.   

Abstract

Reactive oxygen species play an important role in a variety of (patho)physiological vascular processes. Recent publications have produced evidence of a role for putative non-phagocyte NADP oxidase(s) in the vascular production of reactive oxygen species. In the present review, we discuss the detection of the different components of NADP oxidase(s) in the vascular system, together with the putative role of reactive oxygen species produced by vascular NADPH oxidase(s), in both in vitro and in vivo studies.

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Year:  2002        PMID： 12147646      PMCID： PMC1769734          DOI： 10.1136/jcp.55.8.561

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  71 in total

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9.  p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells.

Authors:  M Ushio-Fukai; A M Zafari; T Fukui; N Ishizaka; K K Griendling
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  22 in total

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