| Literature DB >> 7578211 |
T Fukui1, B Lassègue, H Kai, R W Alexander, K K Griendling.
Abstract
Recent studies have shown that the NADPH oxidase participates in the generation of superoxide anion in non-phagocytic cells. Here we report the isolation and nucleotide sequence of a cDNA for the cytochrome b-558 alpha-subunit of the NADPH oxidase in rat vascular smooth muscle cells (VSMCs). The coding region of the cDNA was 93% homologous to mouse and 81% to human in nucleotide sequence and 96% homologous to mouse and 89% to human in the deduced amino acid sequence. Our results provide a tool with which to explore the mechanism of superoxide anion generation in rat VSMCs and other non-phagocytic cells.Entities:
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Year: 1995 PMID： 7578211 DOI： 10.1016/0005-2728(95)00098-4
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002