Literature DB >> 1214009

A comparison of the in vitro activity of metronidazole, tinidazole, and nimorazole against Gram-negative anaerobic bacilli.

A V Reynolds, J M Hamilton-Miller, W Brumfitt.   

Abstract

The in vitro activities of metronidazole, nimorazole, and tinidazole were compared against 69 strains of obligately anaerobic Gram-negative bacilli. Geometric mean MICs were 0-34, 1-05, and 0-28 mug/ml respectively. Thirty-six strains were also tested by the disk method. Correlation between MIC and diameter of the zones of inhibition was poor.

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Year:  1975        PMID： 1214009      PMCID： PMC475858          DOI： 10.1136/jcp.28.10.775

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  22 in total

1.  The selective toxicity of antimicrobial nitroheterocyclic drugs.

Authors:  D I Edwards; M Dye; H Carne
Journal:  J Gen Microbiol       Date:  1973-05

2.  In vitro effect of metronidazole and tinidazole on anaerobic bacteria.

Authors:  K Dornbusch; C E Nord
Journal:  Med Microbiol Immunol       Date:  1974       Impact factor: 3.402

3.  Antibiotic sensitivity testing. Report of an international collaborative study.

Authors:  H M Ericsson; J C Sherris
Journal:  Acta Pathol Microbiol Scand B Microbiol Immunol       Date:  1971

Review 4.  Antiprotozoan activity of nitroimidazoles.

Authors:  I De Carneri
Journal:  Arzneimittelforschung       Date:  1969-03

5.  Bactericidal activity of five antimicrobial agents against Bacteroides fragilis.

Authors:  L J Nastro; S M Finegold
Journal:  J Infect Dis       Date:  1972-07       Impact factor: 5.226

6.  Tinidazole, a new antiprotozoal agent: Effect on Trichomonas and other protozoa.

Authors:  H L Howes; J E Lynch; J L Kivlin
Journal:  Antimicrob Agents Chemother (Bethesda)       Date:  1969

7.  Antimicrobial susceptibilities of anaerobic bacteria: recent clinical isolates.

Authors:  J L Staneck; J A Washington
Journal:  Antimicrob Agents Chemother       Date:  1974-09       Impact factor: 5.191

8.  Bactericidal activity of metronidazole against Bacteroides fragilis.

Authors:  J P Whelan; J H Hale
Journal:  J Clin Pathol       Date:  1973-06       Impact factor: 3.411

9.  Metronidazole versus anaerobes. In vitro data and initial clinical observations.

Authors:  F P Tally; V L Sutter; S M Finegold
Journal:  Calif Med       Date:  1972-12

10.  Newer aminoglycosides--amikacin and tobramycin: an in-vitro comparison with kanamycin and gentamicin.

Authors:  A V Reynolds; J M Hamilton-Miller; W Brumfitt
Journal:  Br Med J       Date:  1974-09-28
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  10 in total

1.  Comparative activity of metronidazole and tinidazole against Clostridium difficile and Peptostreptococcus anaerobius.

Authors:  A M Jokipii; L Jokipii
Journal:  Antimicrob Agents Chemother       Date:  1987-02       Impact factor: 5.191

2.  Susceptibility of anaerobic bacteria to metronidazole, ornidazole, and tinidazole and routine susceptibility testing by standardized methods.

Authors:  J Wust
Journal:  Antimicrob Agents Chemother       Date:  1977-04       Impact factor: 5.191

3.  Bile and serum levels of tinidazole after a single oral dose.

Authors:  P S Hunt; A J Davidson; J Alden; S Cheng
Journal:  Br J Clin Pharmacol       Date:  1982-02       Impact factor: 4.335

4.  Tinidazole: a review of its antiprotozoal activity and therapeutic efficacy.

Authors:  P R Sawyer; R N Brogden; R M Pinder; T M Speight; G S Avery
Journal:  Drugs       Date:  1976       Impact factor: 9.546

5.  Methods for testing antibiotic sensitivity of anaerobic bacteria.

Authors:  J A Garcĭa-Rodriguez; J E Garcĭa-Sánchez; J Prieto-Prieto
Journal:  Infection       Date:  1980       Impact factor: 3.553

6.  Susceptibility of anaerobic bacteria to 23 antimicrobial agents.

Authors:  V L Sutter; S M Finegold
Journal:  Antimicrob Agents Chemother       Date:  1976-10       Impact factor: 5.191

Review 7.  Metronidazole in anaerobic infections: a review of its activity, pharmacokinetics and therapeutic use.

Authors:  R N Brogden; R C Heel; T M Speight; G S Avery
Journal:  Drugs       Date:  1978-11       Impact factor: 9.546

Review 8.  Tinidazole in anaerobic infections: a review of its antibacterial activity, pharmacological properties and therapeutic efficacy.

Authors:  A A Carmine; R N Brogden; R C Heel; T M Speight; G S Avery
Journal:  Drugs       Date:  1982-08       Impact factor: 9.546

9.  Susceptibility of anaerobic bacteria to ten antimicrobial agents.

Authors:  P C Appelbaum; S A Chatterton
Journal:  Antimicrob Agents Chemother       Date:  1978-09       Impact factor: 5.191

10.  Comparative evaluation of the 2-methyl-5-nitroimidazole compounds dimetridazole, metronidazole, secnidazole, ornidazole, tinidazole, carnidazole, and panidazole against Bacteroides fragilis and other bacteria of the Bacteroides fragilis group.

Authors:  L Jokipii; A M Jokipii
Journal:  Antimicrob Agents Chemother       Date:  1985-10       Impact factor: 5.191
  10 in total

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