| Literature DB >> 12110901 |
Abstract
A conserved biological response to double-stranded RNA, known variously as RNA interference (RNAi) or post-transcriptional gene silencing, mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes. RNAi has been cultivated as a means to manipulate gene expression experimentally and to probe gene function on a whole-genome scale.Mesh：
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Year: 2002 PMID： 12110901 DOI： 10.1038/418244a
Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962