Literature DB >> 12584354

Inhibition of gammaherpesvirus replication by RNA interference.

Qingmei Jia1, Ren Sun.   

Abstract

RNA interference (RNAi) is a conserved mechanism in which double-stranded, small interfering RNAs (siRNAs) trigger a sequence-specific gene-silencing process. Here we describe the inhibition of murine herpesvirus 68 replication by siRNAs targeted to sequences encoding Rta, an immediate-early protein known as an initiator of the lytic viral gene expression program, and open reading frame 45 (ORF 45), a conserved viral protein. Our results suggest that RNAi can block gammaherpesvirus replication and ORF 45 is required for efficient viral production.

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Year:  2003        PMID： 12584354      PMCID： PMC149755          DOI： 10.1128/jvi.77.5.3301-3306.2003

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  41 in total

1.  Kaposi's sarcoma-associated herpesvirus latent and lytic gene expression as revealed by DNA arrays.

Authors:  R G Jenner; M M Albà; C Boshoff; P Kellam
Journal:  J Virol       Date:  2001-01       Impact factor: 5.103

2.  Specific interference with gene function by double-stranded RNA in early mouse development.

Authors:  F Wianny; M Zernicka-Goetz
Journal:  Nat Cell Biol       Date:  2000-02       Impact factor: 28.824

3.  RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals.

Authors:  P D Zamore; T Tuschl; P A Sharp; D P Bartel
Journal:  Cell       Date:  2000-03-31       Impact factor: 41.582

4.  Complete sequence and genomic analysis of murine gammaherpesvirus 68.

Authors:  H W Virgin; P Latreille; P Wamsley; K Hallsworth; K E Weck; A J Dal Canto; S H Speck
Journal:  J Virol       Date:  1997-08       Impact factor: 5.103

5.  Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans.

Authors:  A Fire; S Xu; M K Montgomery; S A Kostas; S E Driver; C C Mello
Journal:  Nature       Date:  1998-02-19       Impact factor: 49.962

6.  Transcription mapping of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) genome in a body cavity-based lymphoma cell line (BC-1).

Authors:  R Sarid; O Flore; R A Bohenzky; Y Chang; P S Moore
Journal:  J Virol       Date:  1998-02       Impact factor: 5.103

7.  Transcriptional activation by the product of open reading frame 50 of Kaposi's sarcoma-associated herpesvirus is required for lytic viral reactivation in B cells.

Authors:  D M Lukac; J R Kirshner; D Ganem
Journal:  J Virol       Date:  1999-11       Impact factor: 5.103

8.  A viral gene that activates lytic cycle expression of Kaposi's sarcoma-associated herpesvirus.

Authors:  R Sun; S F Lin; L Gradoville; Y Yuan; F Zhu; G Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-01       Impact factor: 11.205

9.  Epstein-Barr viral latency is disrupted by the immediate-early BRLF1 protein through a cell-specific mechanism.

Authors:  S Zalani; E Holley-Guthrie; S Kenney
Journal:  Proc Natl Acad Sci U S A       Date:  1996-08-20       Impact factor: 11.205

10.  Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease.

Authors:  J Soulier; L Grollet; E Oksenhendler; P Cacoub; D Cazals-Hatem; P Babinet; M F d'Agay; J P Clauvel; M Raphael; L Degos
Journal:  Blood       Date:  1995-08-15       Impact factor: 22.113
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  31 in total

Review 1.  RNA interference: antiviral weapon and beyond.

Authors:  Quan-Chu Wang; Qing-He Nie; Zhi-Hua Feng
Journal:  World J Gastroenterol       Date:  2003-08       Impact factor: 5.742

2.  Inhibition of hepatitis B virus expression and replication by RNA interference in HepG2.2.15.

Authors:  Zhong-Fu Zhao; Hui Yang; De-Wu Han; Long-Feng Zhao; Guo-Ying Zhang; Yun Zhang; Ming-She Liu
Journal:  World J Gastroenterol       Date:  2006-10-07       Impact factor: 5.742

3.  Evidence for CDK-dependent and CDK-independent functions of the murine gammaherpesvirus 68 v-cyclin.

Authors:  Jason W Upton; Samuel H Speck
Journal:  J Virol       Date:  2006-09-27       Impact factor: 5.103

4.  Absence of the uracil DNA glycosylase of murine gammaherpesvirus 68 impairs replication and delays the establishment of latency in vivo.

Authors:  Nana Minkah; Marc Macaluso; Darby G Oldenburg; Clinton R Paden; Douglas W White; Kevin M McBride; Laurie T Krug
Journal:  J Virol       Date:  2015-01-14       Impact factor: 5.103

5.  Murine gammaherpesvirus 68 open reading frame 45 plays an essential role during the immediate-early phase of viral replication.

Authors:  Qingmei Jia; Vasili Chernishof; Eric Bortz; Ian Mchardy; Ting-Ting Wu; Hsiang-I Liao; Ren Sun
Journal:  J Virol       Date:  2005-04       Impact factor: 5.103

6.  RNA interference-mediated virus clearance from cells both acutely and chronically infected with the prototypic arenavirus lymphocytic choriomeningitis virus.

Authors:  Ana B Sánchez; Mar Perez; Tatjana Cornu; Juan Carlos de la Torre
Journal:  J Virol       Date:  2005-09       Impact factor: 5.103

7.  Susceptibility of human hepatitis delta virus RNAs to small interfering RNA action.

Authors:  Jinhong Chang; John M Taylor
Journal:  J Virol       Date:  2003-09       Impact factor: 5.103

Review 8.  Effects of length and location on the cellular response to double-stranded RNA.

Authors:  Qiaoqiao Wang; Gordon G Carmichael
Journal:  Microbiol Mol Biol Rev       Date:  2004-09       Impact factor: 11.056

9.  Inhibition of Epstein-Barr virus (EBV) reactivation by short interfering RNAs targeting p38 mitogen-activated protein kinase or c-myc in EBV-positive epithelial cells.

Authors:  Xiangrong Gao; Haoran Wang; Takeshi Sairenji
Journal:  J Virol       Date:  2004-11       Impact factor: 5.103

10.  Proteins of the secretory pathway govern virus productivity during lytic gammaherpesvirus infection.

Authors:  J Mages; K Freimüller; R Lang; A K Hatzopoulos; S Guggemoos; U H Koszinowski; H Adler
Journal:  J Cell Mol Med       Date:  2008-01-11       Impact factor: 5.310
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