Literature DB >> 12105933

Mechanisms of in situ activation for DNA-targeting antitumor agents.

Scott E Wolkenberg1, Dale L Boger.   

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Year:  2002        PMID: 12105933     DOI: 10.1021/cr010046q

Source DB:  PubMed          Journal:  Chem Rev        ISSN: 0009-2665            Impact factor:   60.622


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  63 in total

1.  A general strategy for target-promoted alkylation in biological systems.

Authors:  Qibing Zhou; Steven E Rokita
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-12       Impact factor: 11.205

2.  Aziridinomitosanes via lactam cyclization.

Authors:  Susan D Wiedner; Edwin Vedejs
Journal:  Org Lett       Date:  2010-09-17       Impact factor: 6.005

3.  Noncovalent DNA binding drives DNA alkylation by leinamycin: evidence that the Z,E-5-(thiazol-4-yl)-penta-2,4-dienone moiety of the natural product serves as an atypical DNA intercalator.

Authors:  Mostafa I Fekry; Jozsef Szekely; Sanjay Dutta; Leonid Breydo; Hong Zang; Kent S Gates
Journal:  J Am Chem Soc       Date:  2011-10-18       Impact factor: 15.419

4.  Synthesis and evaluation of duocarmycin SA analogs incorporating the methyl 1,2,8,8a-tetrahydrocyclopropa[c]oxazolo[2,3-e]indol-4-one-6-carboxylate (COI) alkylation subunit.

Authors:  Kristopher E Boyle; Karen S MacMillan; David A Ellis; James P Lajiness; William M Robertson; Dale L Boger
Journal:  Bioorg Med Chem Lett       Date:  2010-02-02       Impact factor: 2.823

5.  Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity.

Authors:  Mark S Tichenor; Karen S MacMillan; John D Trzupek; Thomas J Rayl; Inkyu Hwang; Dale L Boger
Journal:  J Am Chem Soc       Date:  2007-08-11       Impact factor: 15.419

Review 6.  Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.

Authors:  Christopher J Thibodeaux; Wei-chen Chang; Hung-wen Liu
Journal:  Chem Rev       Date:  2011-10-21       Impact factor: 60.622

Review 7.  An overview of chemical processes that damage cellular DNA: spontaneous hydrolysis, alkylation, and reactions with radicals.

Authors:  Kent S Gates
Journal:  Chem Res Toxicol       Date:  2009-11       Impact factor: 3.739

8.  The Mechanism of Action of (-)-Lomaiviticin A.

Authors:  Seth B Herzon
Journal:  Acc Chem Res       Date:  2017-09-28       Impact factor: 22.384

9.  Directing Quinone Methide-Dependent Alkylation and Cross-Linking of Nucleic Acids with Quaternary Amines.

Authors:  Mark A Hutchinson; Blessing D Deeyaa; Shane R Byrne; Sierra J Williams; Steven E Rokita
Journal:  Bioconjug Chem       Date:  2020-04-23       Impact factor: 4.774

10.  Mitomycins syntheses: a recent update.

Authors:  Jean-Christophe Andrez
Journal:  Beilstein J Org Chem       Date:  2009-07-08       Impact factor: 2.883

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