STUDY OBJECTIVE: To compare cardiac index (CI) measurement by arterial pulse contour analysis using two different algorithms (CI(PC), CI(PCnew)) with pulmonary arterial thermodilution values (CI(PA)) so as to evaluate the difference between the conventional algorithm, CI(PC), and a new algorithm, CI(PCnew), that accounts for patients' individual aortic compliance. DESIGN: Prospective, clinical study. SETTING: Intensive care unit of a university hospital. PATIENTS: 20 ASA physical status II and III patients following elective cardiac surgery. MEASUREMENTS AND MAIN RESULTS: 360 parallel triplicate determinations of CI (CI(PA), CI(PC), CI(PCnew)) were performed within a 90-minute period during the immediate postoperative period. Prior to the start of the study period, CI(PC) as well as CI(PCnew) were calibrated by triplicate femoral arterial thermodilution measurements. Regression analysis of CI(PA) and CI(PC), as well as CI(PA) and CI(PCnew), revealed r = 0.89, p < 0.001, and r = 0.93, p < 0.001, respectively. Bland-Altman analysis was used for determining the accuracy and precision of CI(PC) and CI(PCnew) compared with CI(PA). The mean differences (m) and standard deviation (SD) between CI(PA) and CI(PC,) as well as CI(PA) and CI(PCnew), resulted in m = -0.312 L/min/m(2), SD = 0.456 L/min/m(2), and m = - 0.140 L/min/m(2), SD = 0.328 L/min/m(2), respectively. CONCLUSION: Arterial pulse contour analysis measurement of CI using either algorithm correlates well with CI values derived by pulmonary arterial thermodilution. However, the algorithm introduced in this study proved to be a more accurate predictor of values as derived by pulmonary artery catheter.
STUDY OBJECTIVE: To compare cardiac index (CI) measurement by arterial pulse contour analysis using two different algorithms (CI(PC), CI(PCnew)) with pulmonary arterial thermodilution values (CI(PA)) so as to evaluate the difference between the conventional algorithm, CI(PC), and a new algorithm, CI(PCnew), that accounts for patients' individual aortic compliance. DESIGN: Prospective, clinical study. SETTING: Intensive care unit of a university hospital. PATIENTS: 20 ASA physical status II and III patients following elective cardiac surgery. MEASUREMENTS AND MAIN RESULTS: 360 parallel triplicate determinations of CI (CI(PA), CI(PC), CI(PCnew)) were performed within a 90-minute period during the immediate postoperative period. Prior to the start of the study period, CI(PC) as well as CI(PCnew) were calibrated by triplicate femoral arterial thermodilution measurements. Regression analysis of CI(PA) and CI(PC), as well as CI(PA) and CI(PCnew), revealed r = 0.89, p < 0.001, and r = 0.93, p < 0.001, respectively. Bland-Altman analysis was used for determining the accuracy and precision of CI(PC) and CI(PCnew) compared with CI(PA). The mean differences (m) and standard deviation (SD) between CI(PA) and CI(PC,) as well as CI(PA) and CI(PCnew), resulted in m = -0.312 L/min/m(2), SD = 0.456 L/min/m(2), and m = - 0.140 L/min/m(2), SD = 0.328 L/min/m(2), respectively. CONCLUSION: Arterial pulse contour analysis measurement of CI using either algorithm correlates well with CI values derived by pulmonary arterial thermodilution. However, the algorithm introduced in this study proved to be a more accurate predictor of values as derived by pulmonary artery catheter.
Authors: Daniel A Reuter; Julian Bayerlein; Matthias S G Goepfert; Florian C Weis; Erich Kilger; Peter Lamm; Alwin E Goetz Journal: Intensive Care Med Date: 2003-02-11 Impact factor: 17.440
Authors: M Carl; A Alms; J Braun; A Dongas; J Erb; A Goetz; M Goepfert; W Gogarten; J Grosse; A R Heller; M Heringlake; M Kastrup; A Kroener; S A Loer; G Marggraf; A Markewitz; D Reuter; D V Schmitt; U Schirmer; C Wiesenack; B Zwissler; C Spies Journal: Ger Med Sci Date: 2010-06-15
Authors: Martin Petzoldt; Carsten Riedel; Jan Braeunig; Sebastian Haas; Matthias S Goepfert; Hendrik Treede; Stephan Baldus; Alwin E Goetz; Daniel A Reuter Journal: Intensive Care Med Date: 2013-01-04 Impact factor: 17.440