| Literature DB >> 12069985 |
Laurent Raskine1, Isabelle Borrel, Guilène Barnaud, Sophie Boyer, Béatrice Hanau-Berçot, Jérome Gravisse, Roger Labia, Guillaume Arlet, Marie-José Sanson-Le-Pors.
Abstract
Klebsiella pneumoniae KOL, a clinical strain resistant to various beta-lactams, was isolated from the stools of a patient from Greece. This strain harbored a new pI 9.1 plasmid-mediated AmpC beta-lactamase with unusually high levels of hydrolytic activity for cefoxitin and cefotetan that we named MOX-2. Sequencing of bla(MOX-2) revealed 93.2, 92.9, 92.7, and 73.1% identities with the deduced amino acid sequences of CMY-8, MOX-1, CMY-1, and the AmpC beta-lactamase of Aeromonas sobria, respectively.Entities:
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Year: 2002 PMID: 12069985 PMCID: PMC127302 DOI: 10.1128/AAC.46.7.2262-2265.2002
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191