Literature DB >> 11991658

Human articular chondrocytes express three facilitative glucose transporter isoforms: GLUT1, GLUT3 and GLUT9.

A Mobasheri1, G Neama, S Bell, S Richardson, S D Carter.   

Abstract

Glucose is an important metabolite and a structural precursor for articular cartilage and its transport has significant consequences for cartilage development and functional integrity. In this study the expression of facilitative glucose transporters (GLUTs) in human chondrocytes was investigated. Results showed that at least three GLUT isoforms (GLUT1, GLUT3 and GLUT9) are expressed by normal chondrocytes. Given the central role of glucose in chondrocyte physiology and metabolism, its regular provision via GLUTs will influence the metabolic activity and survival of chondrocytes in cartilage matrices. Copyright 2002 Elsevier Science Ltd. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 11991658     DOI： 10.1006/cbir.2001.0850

Source DB:  PubMed          Journal:  Cell Biol Int        ISSN： 1065-6995            Impact factor:   3.612


  29 in total

1.  Functional characterisation of glucose transport in bovine articular chondrocytes.

Authors:  Robin A J Windhaber; Robert J Wilkins; David Meredith
Journal:  Pflugers Arch       Date:  2003-05-15       Impact factor: 3.657

2.  Facilitative glucose transporter 9, a unique hexose and urate transporter.

Authors:  Manuel Doblado; Kelle H Moley
Journal:  Am J Physiol Endocrinol Metab       Date:  2009-10       Impact factor: 4.310

3.  Porcine intervertebral disc repair using allogeneic juvenile articular chondrocytes or mesenchymal stem cells.

Authors:  Frank L Acosta; Lionel Metz; Huston Davis Adkisson; Jane Liu; Ellen Carruthers-Liebenberg; Curt Milliman; Michael Maloney; Jeffrey C Lotz
Journal:  Tissue Eng Part A       Date:  2011-09-12       Impact factor: 3.845

Review 4.  Type 2 diabetes mellitus and osteoarthritis.

Authors:  Nicola Veronese; Cyrus Cooper; Jean-Yves Reginster; Marc Hochberg; Jaime Branco; Olivier Bruyère; Roland Chapurlat; Nasser Al-Daghri; Elaine Dennison; Gabriel Herrero-Beaumont; Jean-François Kaux; Emmanuel Maheu; René Rizzoli; Roland Roth; Lucio C Rovati; Daniel Uebelhart; Mila Vlaskovska; André Scheen
Journal:  Semin Arthritis Rheum       Date:  2019-01-11       Impact factor: 5.532

5.  Serum Urate Levels Predict Joint Space Narrowing in Non-Gout Patients With Medial Knee Osteoarthritis.

Authors:  Svetlana Krasnokutsky; Charles Oshinsky; Mukundan Attur; Sisi Ma; Hua Zhou; Fangfei Zheng; Meng Chen; Jyoti Patel; Jonathan Samuels; Virginia C Pike; Ravinder Regatte; Jenny Bencardino; Leon Rybak; Steven Abramson; Michael H Pillinger
Journal:  Arthritis Rheumatol       Date:  2017-04-28       Impact factor: 10.995

6.  Assessment of genetic polymorphisms associated with hyperuricemia or gout in the Hmong.

Authors:  Youssef M Roman; Kathleen A Culhane-Pera; Jeremiah Menk; Robert J Straka
Journal:  Per Med       Date:  2016-08-01       Impact factor: 2.512

Review 7.  Gout: a review of nonmodifiable and modifiable risk factors.

Authors:  Lindsey A MacFarlane; Seoyoung C Kim
Journal:  Rheum Dis Clin North Am       Date:  2014-09-02       Impact factor: 2.670

8.  Effects of hexosamines and omega-3/omega-6 fatty acids on pH regulation by interleukin 1-treated isolated bovine articular chondrocytes.

Authors:  Amanda L Tattersall; Robert J Wilkins
Journal:  Pflugers Arch       Date:  2008-01-17       Impact factor: 3.657

9.  Impaired glucose transporter-1 degradation and increased glucose transport and oxidative stress in response to high glucose in chondrocytes from osteoarthritic versus normal human cartilage.

Authors:  Susana C Rosa; Juliana Gonçalves; Fernando Judas; Ali Mobasheri; Celeste Lopes; Alexandrina F Mendes
Journal:  Arthritis Res Ther       Date:  2009-06-02       Impact factor: 5.156

10.  Expression of glucose transporters GLUT-1, GLUT-3, GLUT-9 and HIF-1alpha in normal and degenerate human intervertebral disc.

Authors:  S M Richardson; R Knowles; J Tyler; A Mobasheri; J A Hoyland
Journal:  Histochem Cell Biol       Date:  2008-01-03       Impact factor: 4.304
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.