Literature DB >> 11981209

Results of 281 consecutive total laparoscopic Roux-en-Y gastric bypasses to treat morbid obesity.

Eric J DeMaria1, Harvey J Sugerman, John M Kellum, Jill G Meador, Luke G Wolfe.   

Abstract

OBJECTIVE: To determine the safety and efficacy of laparoscopic Roux-en-Y gastric bypass for the treatment of morbid obesity. SUMMARY BACKGROUND DATA: Laparoscopic Roux-en-Y gastric bypass is a new and technically challenging surgical procedure that requires careful study.
METHODS: The authors attempted total laparoscopic Roux-en-Y gastric bypass in 281 consecutive patients. Procedures included 175 proximal bypasses, 12 long-limb bypasses, and 9 revisional procedures from previous bariatric operations. The gastrojejunostomy and jejunojejunostomy were primarily constructed using linear stapling techniques.
RESULTS: Eight patients required conversion to an open procedure (2.8%). The mean age of the patients was 41.6 years (range 15-71) and 87% were female. The mean preoperative body mass index was 48.1 kg/m2. The operative time decreased significantly from 234 +/- 77 minutes in the first quartile to 162 +/- 42 minutes in the most recent quartile. Postoperative length of stay averaged 4 days (range 2-91), with 75% of patients discharged within 3 days. The median hospital stay was 2 days. No patient died after surgery. Complications included three (1.5%) major wound infections (each followed a reoperation for a complication or open conversion), incisional hernia in 5 patients (1.8%), and anastomotic leak with peritonitis in 14 patients (5.1%). Three gastrojejunal leaks were managed without surgery, four by laparoscopic repair/drainage, and three by open repair/drainage. Only three patients had anastomotic leaks in the most recent 164 procedures (1.8%) since the routine use of a two-layer anastomotic technique. Data at 1 year after surgery were available in 69 of 96 (72%) patients (excludes revisions). Weight loss at one year was 70 +/- 5% of excess weight. Most comorbid conditions resolved by 1 year after surgery; notably, 88% of patients with diabetes no longer required medications.
CONCLUSIONS: Laparoscopic gastric bypass demonstrates excellent weight loss and resolution of comorbidities with a low complication rate. The learning curve is evident: operative time and leaks decreased with experience and improved techniques. The primary advantage is an extremely low risk of wound complications, including infection and hernia.

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Mesh:

Year:  2002        PMID: 11981209      PMCID: PMC1422489          DOI: 10.1097/00000658-200205000-00005

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  11 in total

1.  Laparoscopic Gastric Bypass, Roux-en-Y: Preliminary Report of Five Cases.

Authors: 
Journal:  Obes Surg       Date:  1994-11       Impact factor: 4.129

2.  A comparison study of laparoscopic versus open gastric bypass for morbid obesity.

Authors:  N T Nguyen; H S Ho; L S Palmer; B M Wolfe
Journal:  J Am Coll Surg       Date:  2000-08       Impact factor: 6.113

Review 3.  Gastric bypass for treating severe obesity.

Authors:  H J Sugerman; J M Kellum; K M Engle; L Wolfe; J V Starkey; R Birkenhauer; P Fletcher; M J Sawyer
Journal:  Am J Clin Nutr       Date:  1992-02       Impact factor: 7.045

4.  Outcomes after laparoscopic Roux-en-Y gastric bypass for morbid obesity.

Authors:  P R Schauer; S Ikramuddin; W Gourash; R Ramanathan; J Luketich
Journal:  Ann Surg       Date:  2000-10       Impact factor: 12.969

5.  Laparoscopic Roux-en-Y gastric bypass for morbid obesity: technique and preliminary results of our first 400 patients.

Authors:  K D Higa; K B Boone; T Ho; O G Davies
Journal:  Arch Surg       Date:  2000-09

6.  Laparoscopic gastric bypass, Roux-en-Y- 500 patients: technique and results, with 3-60 month follow-up.

Authors:  A C Wittgrove; G W Clark
Journal:  Obes Surg       Date:  2000-06       Impact factor: 4.129

Review 7.  Gastric bypass.

Authors:  R E Brolin
Journal:  Surg Clin North Am       Date:  2001-10       Impact factor: 2.741

8.  Surgical treatment of obesity and its effect on diabetes: 10-y follow-up.

Authors:  W J Pories; K G MacDonald; E J Morgan; M K Sinha; G L Dohm; M S Swanson; H A Barakat; P G Khazanie; N Leggett-Frazier; S D Long
Journal:  Am J Clin Nutr       Date:  1992-02       Impact factor: 7.045

9.  A randomized prospective trial of gastric bypass versus vertical banded gastroplasty for morbid obesity and their effects on sweets versus non-sweets eaters.

Authors:  H J Sugerman; J V Starkey; R Birkenhauer
Journal:  Ann Surg       Date:  1987-06       Impact factor: 12.969

10.  A multicenter, placebo-controlled, randomized, double-blind, prospective trial of prophylactic ursodiol for the prevention of gallstone formation following gastric-bypass-induced rapid weight loss.

Authors:  H J Sugerman; W H Brewer; M L Shiffman; R E Brolin; M A Fobi; J H Linner; K G MacDonald; A M MacGregor; L F Martin; J C Oram-Smith
Journal:  Am J Surg       Date:  1995-01       Impact factor: 2.565

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  148 in total

1.  Clinical predictors of leak after laparoscopic Roux-en-Y gastric bypass for morbid obesity.

Authors:  E C Hamilton; T L Sims; T T Hamilton; M A Mullican; D B Jones; D A Provost
Journal:  Surg Endosc       Date:  2003-03-07       Impact factor: 4.584

2.  Laparoscopic Roux-en-Y gastric bypass: comparison between hand-sewn and mechanical gastrojejunostomy.

Authors:  Julien Jarry; Tristan Wagner; Marie de Pommerol; Antonio Sa Cunha; Denis Collet
Journal:  Updates Surg       Date:  2011-12-14

Review 3.  Experience with over 3,000 open and laparoscopic bariatric procedures: multivariate analysis of factors related to leak and resultant mortality.

Authors:  A Z Fernandez; E J DeMaria; D S Tichansky; J M Kellum; L G Wolfe; J Meador; H J Sugerman
Journal:  Surg Endosc       Date:  2003-12-29       Impact factor: 4.584

4.  Open and laparoscopic surgical modalities for the management of obesity.

Authors:  Philip R Schauer
Journal:  J Gastrointest Surg       Date:  2003 May-Jun       Impact factor: 3.452

5.  Laparoscopic Roux-en-Y gastric bypass, but not rebanding, should be proposed as rescue procedure for patients with failed laparoscopic gastric banding.

Authors:  Markus Weber; Markus K Müller; Jean-Marie Michel; Rahim Belal; Fritz Horber; Renward Hauser; Pierre-Alain Clavien
Journal:  Ann Surg       Date:  2003-12       Impact factor: 12.969

6.  Gastric banding.

Authors:  John M Kellum
Journal:  Ann Surg       Date:  2003-01       Impact factor: 12.969

Review 7.  Roux-en-Y gastric bypass is the operation of choice for bariatric surgery.

Authors:  W Scott Melvin
Journal:  J Gastrointest Surg       Date:  2004 May-Jun       Impact factor: 3.452

8.  Effect of duodenal-jejunal exclusion in a non-obese animal model of type 2 diabetes: a new perspective for an old disease.

Authors:  Alberto Patriti; Enrico Facchiano; Annibale Donini
Journal:  Ann Surg       Date:  2004-08       Impact factor: 12.969

9.  Learning curve for laparoscopic Roux-en-Y gastric bypass with totally hand-sewn anastomosis: analysis of first 600 consecutive patients.

Authors:  C Ballesta-López; I Poves; M Cabrera; J A Almeida; G Macías
Journal:  Surg Endosc       Date:  2005-03-08       Impact factor: 4.584

10.  Effect of laparoscopic Roux-en-Y gastric bypass on body composition and insulin resistance in Chinese patients with type 2 diabetes mellitus.

Authors:  Weizheng Li; Liyong Zhu; Zhaohui Mo; Xiangwu Yang; Guohui Wang; Pengzhou Li; Juan Tan; Fei Ye; Jeff Strain; Ibrahim Im; Shaihong Zhu
Journal:  Obes Surg       Date:  2014-04       Impact factor: 4.129

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