| Literature DB >> 11958988 |
Sanghee Kim1, Eunkyung Kim, Dong Sun Shin, Heonjoong Kang, Ki Bong Oh.
Abstract
A series of farnesoic acid derivatives was prepared and their morphogenic regulatory activities were evaluated. Their inhibitory activities against yeast cell growth and yeast-to-hypha transition examined in Candida albicans cells are dependent upon the chain length as well as the substitution patterns on the isoprenoid template. The preliminary structure-activity relationship of these compounds is described to elucidate the essential structural requirements.Entities:
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Year: 2002 PMID: 11958988 DOI: 10.1016/s0960-894x(02)00038-0
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823