Literature DB >> 11950343

2,6-diaminopurine in TNA: effect on duplex stabilities and on the efficiency of template-controlled ligations.

Xiaolin Wu1, Guillermo Delgado, Ramanarayanan Krishnamurthy, Albert Eschenmoser.   

Abstract

Replacement of adenine by 2,6-diaminopurine-two nucleobases to be considered equivalent from an etiological point of view-strongly enhances the stability of TNA/TNA, TNA/RNA, or TNA/DNA duplexes and efficiently accelerates template-directed ligation of TNA ligands. [reaction: see text]

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Year:  2002        PMID： 11950343     DOI： 10.1021/ol020016p

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  13 in total

1.  The TNA-family of nucleic acid systems: properties and prospects.

Authors:  Albert Eschenmoser
Journal:  Orig Life Evol Biosph       Date:  2004-06       Impact factor: 1.950

2.  Darwinian evolution of an alternative genetic system provides support for TNA as an RNA progenitor.

Authors:  Hanyang Yu; Su Zhang; John C Chaput
Journal:  Nat Chem       Date:  2012-01-10       Impact factor: 24.427

3.  Enzymatic Synthesis of Sequence-Defined Synthetic Nucleic Acid Polymers with Diverse Functional Groups.

Authors:  Dehui Kong; Yi Lei; Wayland Yeung; Ryan Hili
Journal:  Angew Chem Int Ed Engl       Date:  2016-10-10       Impact factor: 15.336

4.  High fidelity TNA synthesis by Therminator polymerase.

Authors:  Justin K Ichida; Allen Horhota; Keyong Zou; Larry W McLaughlin; Jack W Szostak
Journal:  Nucleic Acids Res       Date:  2005-09-12       Impact factor: 16.971

5.  Synthesis and nonenzymatic template-directed polymerization of 2'-amino-2'-deoxythreose nucleotides.

Authors:  J Craig Blain; Alonso Ricardo; Jack W Szostak
Journal:  J Am Chem Soc       Date:  2014-01-22       Impact factor: 15.419

6.  Kinetic analysis of an efficient DNA-dependent TNA polymerase.

Authors:  Allen Horhota; Keyong Zou; Justin K Ichida; Biao Yu; Larry W McLaughlin; Jack W Szostak; John C Chaput
Journal:  J Am Chem Soc       Date:  2005-05-25       Impact factor: 15.419

7.  Synthesis of alpha-L-threofuranosyl nucleoside triphosphates (tNTPs).

Authors:  Keyong Zou; Allen Horhota; Biao Yu; Jack W Szostak; Larry W McLaughlin
Journal:  Org Lett       Date:  2005-04-14       Impact factor: 6.005

8.  Primer fabrication using polymerase mediated oligonucleotide synthesis.

Authors:  Murray J Cairns; Torsten Thomas; Carolina E Beltran; Daniel Tillett
Journal:  BMC Genomics       Date:  2009-07-31       Impact factor: 3.969

9.  An in vitro selection system for TNA.

Authors:  Justin K Ichida; Keyong Zou; Allen Horhota; Biao Yu; Larry W McLaughlin; Jack W Szostak
Journal:  J Am Chem Soc       Date:  2005-03-09       Impact factor: 15.419

10.  The role of sugar-backbone heterogeneity and chimeras in the simultaneous emergence of RNA and DNA.

Authors:  Subhendu Bhowmik; Ramanarayanan Krishnamurthy
Journal:  Nat Chem       Date:  2019-09-16       Impact factor: 24.427
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