Literature DB >> 11926312

Scytonemin--a marine natural product inhibitor of kinases key in hyperproliferative inflammatory diseases.

C S Stevenson1, E A Capper, A K Roshak, B Marquez, K Grace, W H Gerwick, R S Jacobs, L A Marshall.   

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Year:  2002        PMID： 11926312     DOI： 10.1007/BF02684014

Source DB:  PubMed          Journal:  Inflamm Res        ISSN： 1023-3830            Impact factor:   4.575


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  8 in total

1.  The human polo-like kinase, PLK, regulates cdc2/cyclin B through phosphorylation and activation of the cdc25C phosphatase.

Authors:  A K Roshak; E A Capper; C Imburgia; J Fornwald; G Scott; L A Marshall
Journal:  Cell Signal       Date:  2000-06       Impact factor: 4.315

2.  Isozymic forms of rat brain Ca2+-activated and phospholipid-dependent protein kinase.

Authors:  K P Huang; H Nakabayashi; F L Huang
Journal:  Proc Natl Acad Sci U S A       Date:  1986-11       Impact factor: 11.205

Review 3.  Protein kinase C in cell signaling: strategies for the development of selective inhibitors.

Authors:  P M Blumberg; G Acs; P Acs; L B Areces; M G Kazanietz; N E Lewin; Z Szallasi
Journal:  Agents Actions Suppl       Date:  1995

4.  The structure of scytonemin, an ultraviolet sunscreen pigment from the sheaths of cyanobacteria.

Authors:  P J Proteau; W H Gerwick; F Garcia-Pichel; R Castenholz
Journal:  Experientia       Date:  1993-09-15

5.  Anti-inflammatory properties of the protein kinase C inhibitor, 3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H- pyrrole-2,5-dione monohydrochloride (GF109203X) in the PMA-mouse ear edema model.

Authors:  S Kuchera; H Barth; P Jacobson; A Metz; C Schaechtele; D Schrier
Journal:  Agents Actions       Date:  1993

6.  Anti-human RP105 sera induces lymphocyte proliferation.

Authors:  A K Roshak; K M Anderson; S D Holmes; Z Jonak; B Bolognese; J Terrett; L A Marshall
Journal:  J Leukoc Biol       Date:  1999-01       Impact factor: 4.962

7.  The cdc25 protein controls tyrosine dephosphorylation of the cdc2 protein in a cell-free system.

Authors:  A Kumagai; W G Dunphy
Journal:  Cell       Date:  1991-03-08       Impact factor: 41.582

8.  Fuscoside: an anti-inflammatory marine natural product which selectively inhibits 5-lipoxygenase. Part I: Physiological and biochemical studies in murine inflammatory models.

Authors:  P B Jacobson; R S Jacobs
Journal:  J Pharmacol Exp Ther       Date:  1992-08       Impact factor: 4.030
  8 in total
  30 in total

Review 1.  Microbial pigments as natural color sources: current trends and future perspectives.

Authors:  Hardeep S Tuli; Prachi Chaudhary; Vikas Beniwal; Anil K Sharma
Journal:  J Food Sci Technol       Date:  2014-10-10       Impact factor: 2.701

Review 2.  Marine pharmacology in 2001--2002: marine compounds with anthelmintic, antibacterial, anticoagulant, antidiabetic, antifungal, anti-inflammatory, antimalarial, antiplatelet, antiprotozoal, antituberculosis, and antiviral activities; affecting the cardiovascular, immune and nervous systems and other miscellaneous mechanisms of action.

Authors:  Alejandro M S Mayer; Mark T Hamann
Journal:  Comp Biochem Physiol C Toxicol Pharmacol       Date:  2005 Mar-Apr       Impact factor: 3.228

3.  Molecular genetics and genomic analysis of scytonemin biosynthesis in Nostoc punctiforme ATCC 29133.

Authors:  Tanya Soule; V Stout; W D Swingley; J C Meeks; F Garcia-Pichel
Journal:  J Bacteriol       Date:  2007-03-09       Impact factor: 3.490

4.  Organization, evolution, and expression analysis of the biosynthetic gene cluster for scytonemin, a cyanobacterial UV-absorbing pigment.

Authors:  Carla M Sorrels; Philip J Proteau; William H Gerwick
Journal:  Appl Environ Microbiol       Date:  2009-05-29       Impact factor: 4.792

5.  Probing the in vivo biosynthesis of scytonemin, a cyanobacterial ultraviolet radiation sunscreen, through small scale stable isotope incubation studies and MALDI-TOF mass spectrometry.

Authors:  Carla S Jones; Eduardo Esquenazi; Pieter C Dorrestein; William H Gerwick
Journal:  Bioorg Med Chem       Date:  2011-06-14       Impact factor: 3.641

6.  Investigating the initial steps in the biosynthesis of cyanobacterial sunscreen scytonemin.

Authors:  Emily P Balskus; Christopher T Walsh
Journal:  J Am Chem Soc       Date:  2008-10-28       Impact factor: 15.419

7.  Selective MyD88-dependent pathway inhibition by the cyanobacterial natural product malyngamide F acetate.

Authors:  Francisco A Villa; Kelly Lieske; Lena Gerwick
Journal:  Eur J Pharmacol       Date:  2009-12-16       Impact factor: 4.432

8.  Scytonemin inhibits cell proliferation and arrests cell cycle through downregulating Plk1 activity in multiple myeloma cells.

Authors:  Guojun Zhang; Zhe Zhang; Zhuogang Liu
Journal:  Tumour Biol       Date:  2013-04-13

9.  An enzymatic cyclopentyl[b]indole formation involved in scytonemin biosynthesis.

Authors:  Emily P Balskus; Christopher T Walsh
Journal:  J Am Chem Soc       Date:  2009-10-21       Impact factor: 15.419

10.  A comparative genomics approach to understanding the biosynthesis of the sunscreen scytonemin in cyanobacteria.

Authors:  Tanya Soule; Kendra Palmer; Qunjie Gao; Ruth M Potrafka; Valerie Stout; Ferran Garcia-Pichel
Journal:  BMC Genomics       Date:  2009-07-24       Impact factor: 3.969
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