| Literature DB >> 11908974 |
Giovanni Appendino1, Federica Bianchi, Alberto Minassi, Olov Sterner, Mauro Ballero, Simon Gibbons.
Abstract
The dimeric nonprenylated acylphloroglucinol semimyrtucommulone (6) was obtained from the leaves of myrtle (Myrtus communis) as a 2:1 mixture of two rotamers. The known trimeric phloroglucinol myrtucommulone A (1) was also isolated and characterized spectroscopically as a silylated cyclized derivative (5). Myrtucommulone A showed significant antibacterial activity against multidrug-resistant (MDR) clinically relevant bacteria, while semimyrtucommulone was less active.Entities:
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Year: 2002 PMID： 11908974 DOI： 10.1021/np010441b
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050