Literature DB >> 11899477

D-amino-acid oxidase--an improved production of the enzyme by the yeast Trigonopsis variabilis in a laboratory fermentor.

P Kujan1, A Prell, H Safár, P Holler, K Plhácková, M Sobotka.   

Abstract

The cultivation of the yeast Trigonopsis variabilis producing D-amino-acid oxidase (an enzyme participating in the transformation of cephalosporin C into 7-aminocephalosporanic acid for the production of beta-lactam antibiotics) was controlled by changes of dissolved oxygen tension and extended fermentation times. The production technology was optimized on a laboratory scale and scale-up parameters were identified.

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Year:  2001        PMID： 11899477     DOI： 10.1007/bf02814434

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN： 0015-5632            Impact factor:   2.099


  8 in total

1.  Transaminase and D-amino acid oxidase of Trigonopsis variabilis.

Authors:  S SENTHESHANMUGANATHAN; W J NICKERSON
Journal:  J Gen Microbiol       Date:  1962-03

2.  Production of L-amino acids by applying D-amino acid oxidases.

Authors:  L Fischer; R Hörner; F Wagner
Journal:  Ann N Y Acad Sci       Date:  1995-03-31       Impact factor: 5.691

3.  Characterization of D-amino acid oxidase from Trigonopsis variabilis.

Authors:  L Pollegioni; S Butò; W Tischer; S Ghisla; M S Pilone
Journal:  Biochem Mol Biol Int       Date:  1993-11

4.  Production of a new D-amino acid oxidase from the fungus Fusarium oxysporum.

Authors:  M Gabler; L Fischer
Journal:  Appl Environ Microbiol       Date:  1999-08       Impact factor: 4.792

5.  Stabilization of D-amino-acid oxidase from Trigonopsis variabilis by manganese dioxide.

Authors:  A Vikartovská-Welwardová; E Michalková; P Gemeiner; L Welward
Journal:  Folia Microbiol (Praha)       Date:  1999       Impact factor: 2.099

6.  A D-amino acid oxidase from Chlorella vulgaris.

Authors:  E K Pistorius; H Voss
Journal:  Biochim Biophys Acta       Date:  1977-04-12

7.  Regulation of L-amino acid oxidase and of D-amino acid oxidase in Neurospora crassa.

Authors:  L Sikora; G A Marzluf
Journal:  Mol Gen Genet       Date:  1982

8.  Production of α-keto acids Part I. Immobilized cells ofTrigonopsis variabilis containing D-amino acid oxidase.

Authors:  P Brodelius; K Nilsson; K Mosbach
Journal:  Appl Biochem Biotechnol       Date:  1981-12       Impact factor: 2.926
  8 in total

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