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Literature DB >> 11891119

Regulation of cell polarity during eukaryotic chemotaxis: the chemotactic compass.

Abstract

Phosphatidylinositol 3-kinase lipid products and the Rho GTPases play a central role in transmitting information from chemotactic receptors to the effectors of cell polarity, and recent advances in the field have allowed us to understand these roles more clearly. Emergent properties of positive and negative regulation of these molecules may account for the establishment of cell polarity during chemotaxis for a wide range of cells from Dictyostelium to fibroblasts to neutrophils.

Mesh：

Substances：

Year: 2002 PMID： 11891119 PMCID： PMC2819118 DOI： 10.1016/s0955-0674(02)00310-1

Source DB: PubMed Journal: Curr Opin Cell Biol ISSN： 0955-0674 Impact factor: 8.382

43 in total

1. Dissociation of chemotaxis from agonist-induced receptor internalization in a lymphocyte cell line transfected with CCR2B. Evidence that directed migration does not require rapid modulation of signaling at the receptor level.

Authors: H Arai; F S Monteclaro; C L Tsou; C Franci; I F Charo
Journal: J Biol Chem Date: 1997-10-03 Impact factor: 5.157

2. The lipid products of phosphoinositide 3-kinase increase cell motility through protein kinase C.

Authors: M P Derman; A Toker; J H Hartwig; K Spokes; J R Falck; C S Chen; L C Cantley; L G Cantley
Journal: J Biol Chem Date: 1997-03-07 Impact factor: 5.157

3. Phosphorylation of chemoattractant receptors is not essential for chemotaxis or termination of G-protein-mediated responses.

Authors: J Y Kim; R D Soede; P Schaap; R Valkema; J A Borleis; P J Van Haastert; P N Devreotes; D Hereld
Journal: J Biol Chem Date: 1997-10-24 Impact factor: 5.157

4. The phosphatidylinositol 3-kinase inhibitor wortmannin markedly reduces chemotactic peptide-induced locomotion and increases in cytoskeletal actin in human neutrophils.

Authors: V Niggli; H Keller
Journal: Eur J Pharmacol Date: 1997-09-17 Impact factor: 4.432

5. PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase.

Authors: P T Hawkins; A Eguinoa; R G Qiu; D Stokoe; F T Cooke; R Walters; S Wennström; L Claesson-Welsh; T Evans; M Symons
Journal: Curr Biol Date: 1995-04-01 Impact factor: 10.834

6. Rho family GTPases bind to phosphoinositide kinases.

Authors: K F Tolias; L C Cantley; C L Carpenter
Journal: J Biol Chem Date: 1995-07-28 Impact factor: 5.157

7. Rac GTPase interacts specifically with phosphatidylinositol 3-kinase.

Authors: G M Bokoch; C J Vlahos; Y Wang; U G Knaus; A E Traynor-Kaplan
Journal: Biochem J Date: 1996-05-01 Impact factor: 3.857

8. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN.

Authors: V Stambolic; A Suzuki; J L de la Pompa; G M Brothers; C Mirtsos; T Sasaki; J Ruland; J M Penninger; D P Siderovski; T W Mak
Journal: Cell Date: 1998-10-02 Impact factor: 41.582

9. Dynamic distribution of chemoattractant receptors in living cells during chemotaxis and persistent stimulation.

Authors: Z Xiao; N Zhang; D B Murphy; P N Devreotes
Journal: J Cell Biol Date: 1997-10-20 Impact factor: 10.539

10. A role for Cdc42 in macrophage chemotaxis.

Authors: W E Allen; D Zicha; A J Ridley; G E Jones
Journal: J Cell Biol Date: 1998-06-01 Impact factor: 10.539

100 in total

1. Spatial analysis of 3' phosphoinositide signaling in living fibroblasts: II. Parameter estimates for individual cells from experiments.

Authors: Ian C Schneider; Jason M Haugh
Journal: Biophys J Date: 2004-01 Impact factor: 4.033

2. Spatial analysis of 3' phosphoinositide signaling in living fibroblasts: I. Uniform stimulation model and bounds on dimensionless groups.

Authors: Jason M Haugh; Ian C Schneider
Journal: Biophys J Date: 2004-01 Impact factor: 4.033

3. Receptor-mediated regulation of PI3Ks confines PI(3,4,5)P3 to the leading edge of chemotaxing cells.

Authors: Yi Elaine Huang; Miho Iijima; Carole A Parent; Satoru Funamoto; Richard A Firtel; Peter Devreotes
Journal: Mol Biol Cell Date: 2003-02-06 Impact factor: 4.138

Review 4. Molecular control of neuronal migration.

Authors: Hwan Tae Park; Jane Wu; Yi Rao
Journal: Bioessays Date: 2002-09 Impact factor: 4.345

5. Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton.

Authors: Chris Janetopoulos; Lan Ma; Peter N Devreotes; Pablo A Iglesias
Journal: Proc Natl Acad Sci U S A Date: 2004-06-07 Impact factor: 11.205

6. The genetics of geometry.

Authors: Enrico Coen; Anne-Gaëlle Rolland-Lagan; Mark Matthews; J Andrew Bangham; Przemyslaw Prusinkiewicz
Journal: Proc Natl Acad Sci U S A Date: 2004-02-11 Impact factor: 11.205

Review 7. Knowledge translation: airway epithelial cell migration and respiratory diseases.

Authors: Helan Xiao; Debbie X Li; Mingyao Liu
Journal: Cell Mol Life Sci Date: 2012-06-21 Impact factor: 9.261

8. Rac activation: P-Rex1 - a convergence point for PIP(3) and Gbetagamma?

Authors: Orion D Weiner
Journal: Curr Biol Date: 2002-06-25 Impact factor: 10.834

9. Mesenchymal chemotaxis requires selective inactivation of myosin II at the leading edge via a noncanonical PLCγ/PKCα pathway.

Authors: Sreeja B Asokan; Heath E Johnson; Anisur Rahman; Samantha J King; Jeremy D Rotty; Irina P Lebedeva; Jason M Haugh; James E Bear
Journal: Dev Cell Date: 2014-12-04 Impact factor: 12.270

Review 10. Axon guidance: asymmetric signaling orients polarized outgrowth.

Authors: Christopher C Quinn; William G Wadsworth
Journal: Trends Cell Biol Date: 2008-10-24 Impact factor: 20.808