Literature DB >> 6771337

Antibody-dependent cell-mediated antibacterial activity of human mononuclear cells. II. Immune specificity of antimeningococcal activity.

L F Smith, G H Lowell.   

Abstract

Antibody-dependent activity against group C meningococci mediated by human mononuclear cells or purified lymphocytes was inhibited when sera from adults immunized with group C meningococcal polysaccharide were preincubated with that polysaccharide. Likewise, activity against group A meningococci induced by heat-inactivated sera from adults immunized with group A meningococcal polysaccharide was inhibited by preincubation with that polysaccharide. Neither heterologous polysaccharide nor homologous protein or lipopolysaccharide meningococcal antigens inhibited the activity of either of these sera. The data indicate that immune specificity in this cell-mediated antibacterial system is dependent upon antibodies to the specific polysaccharide antigen with which the serum donor had been immunized.

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Year:  1980        PMID： 6771337     DOI： 10.1093/infdis/141.6.748

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  6 in total

1.  Opsonophagocytosis of fluorescent polystyrene beads coupled to Neisseria meningitidis serogroup A, C, Y, or W135 polysaccharide correlates with serum bactericidal activity.

Authors:  Joseph Martinez; Tamara Pilishvili; Suzanne Barnard; Joseph Caba; Willie Spear; Sandra Romero-Steiner; George M Carlone
Journal:  Clin Diagn Lab Immunol       Date:  2002-03

Review 2.  Cellular immune responses during gonococcal and meningococcal infections.

Authors:  M D Cooper; E J Moticka
Journal:  Clin Microbiol Rev       Date:  1989-04       Impact factor: 26.132

3.  The (alpha2-->8)-linked polysialic acid capsule of group B Neisseria meningitidis modifies multiple steps during interaction with human macrophages.

Authors:  R C Read; S Zimmerli; C Broaddus; D A Sanan; D S Stephens; J D Ernst
Journal:  Infect Immun       Date:  1996-08       Impact factor: 3.441

4.  Investigation of different group A immunoassays following one dose of meningococcal group A conjugate vaccine or A/C polysaccharide vaccine in adults.

Authors:  H Findlow; B D Plikaytis; A Aase; M C Bash; H Chadha; C Elie; G Laher; J Martinez; T Herstad; E Newton; S Viviani; C Papaspyridis; P Kulkarni; M Wilding; M P Preziosi; E Marchetti; M Hassan-King; F M La Force; G Carlone; R Borrow
Journal:  Clin Vaccine Immunol       Date:  2009-05-27

5.  Pretreatment with lipoteichoic acid sensitizes target cells to antibody-dependent cellular cytotoxicity in the presence of anti-lipoteichoic acid antibodies.

Authors:  D E Lopatin; R E Kessler
Journal:  Infect Immun       Date:  1985-06       Impact factor: 3.441

6.  IgA-dependent, monocyte-mediated, antibacterial activity.

Authors:  G H Lowell; L F Smith; J M Griffiss; B L Brandt
Journal:  J Exp Med       Date:  1980-08-01       Impact factor: 14.307
  6 in total

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