Literature DB >> 11871893

Total synthesis of the ethyl ester of the major urinary metabolite of prostaglandin E(2).

Douglass F Taber1, Dawei Teng.   

Abstract

The preparation of the ethyl ester of the major urinary metabolite of prostaglandin E(2) 3 is described. The key step is the kinetic opening of the TBS-protected bicyclic ketone 7 with thiophenol.

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Year:  2002        PMID： 11871893     DOI： 10.1021/jo011017i

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  5 in total

1.  Levels of prostaglandin E metabolite, the major urinary metabolite of prostaglandin E2, are increased in smokers.

Authors:  Neil D Gross; Jay O Boyle; Jason D Morrow; Myles K Williams; Chaya S Moskowitz; Kotha Subbaramaiah; Andrew J Dannenberg; Anna J Duffield-Lillico
Journal:  Clin Cancer Res       Date:  2005-08-15       Impact factor: 12.531

2.  Rh-catalyzed intermolecular reactions of cyclic α-diazocarbonyl compounds with selectivity over tertiary C-H bond migration.

Authors:  Andrew DeAngelis; Olga Dmitrenko; Joseph M Fox
Journal:  J Am Chem Soc       Date:  2012-06-19       Impact factor: 15.419

3.  Preparation of the Major Urinary Metabolite of (-)-Prostaglandin E(2).

Authors:  Douglass F Taber; Peiming Gu
Journal:  Tetrahedron       Date:  2009-08-01       Impact factor: 2.457

4.  Effect of zileuton and celecoxib on urinary LTE4 and PGE-M levels in smokers.

Authors:  Arash Mohebati; Ginger L Milne; Xi Kathy Zhou; Anna J Duffield-Lillico; Jay O Boyle; Allison Knutson; Brian P Bosworth; Philip J Kingsley; Lawrence J Marnett; Powel H Brown; Esther G Akpa; Eva Szabo; Andrew J Dannenberg
Journal:  Cancer Prev Res (Phila)       Date:  2013-05-16

5.  Effect of Dysglycemia on Urinary Lipid Mediator Profiles in Persons With Pulmonary Tuberculosis.

Authors:  María B Arriaga; Farina Karim; Artur T L Queiroz; Mariana Araújo-Pereira; Beatriz Barreto-Duarte; Caio Sales; Mahomed-Yunus S Moosa; Matilda Mazibuko; Ginger L Milne; Fernanda Maruri; Carlos Henrique Serezani; John R Koethe; Marina C Figueiredo; Afrânio L Kritski; Marcelo Cordeiro-Santos; Valeria C Rolla; Timothy R Sterling; Alasdair Leslie; Bruno B Andrade
Journal:  Front Immunol       Date:  2022-07-08       Impact factor: 8.786
  5 in total

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