Literature DB >> 11867675

The role of growth hormone in T-cell development and reconstitution.

Lisbeth A Welniak1, Rui Sun, William J Murphy.   

Abstract

Growth hormone (GH), directly or through GH-induction of insulin-like growth factor (IGF)-1, has been implicated in lymphocyte development and function. Recent studies have questioned the role of GH and IGF-1 in immune responses. This review examines experimental data describing the immunoregulatory function of GH and attempts to reconcile the literature.

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Year:  2002        PMID： 11867675

Source DB:  PubMed          Journal:  J Leukoc Biol        ISSN： 0741-5400            Impact factor:   4.962


  23 in total

1.  Association of CD4+ T-lymphocyte counts and new thymic emigrants in HIV-infected children during successful highly active antiretroviral therapy.

Authors:  Akihiko Saitoh; Kumud K Singh; Sharsti Sandall; Christine A Powell; Terrence Fenton; Courtney V Fletcher; Karen Hsia; Stephen A Spector
Journal:  J Allergy Clin Immunol       Date:  2006-04       Impact factor: 10.793

Review 2.  Rejuvenation of the aging thymus: growth hormone-mediated and ghrelin-mediated signaling pathways.

Authors:  Dennis D Taub; William J Murphy; Dan L Longo
Journal:  Curr Opin Pharmacol       Date:  2010-06-04       Impact factor: 5.547

3.  Development of a diverse human T-cell repertoire despite stringent restriction of hematopoietic clonality in the thymus.

Authors:  Martijn H Brugman; Anna-Sophia Wiekmeijer; Marja van Eggermond; Ingrid Wolvers-Tettero; Anton W Langerak; Edwin F E de Haas; Leonid V Bystrykh; Jon J van Rood; Gerald de Haan; Willem E Fibbe; Frank J T Staal
Journal:  Proc Natl Acad Sci U S A       Date:  2015-10-19       Impact factor: 11.205

4.  Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8 T cells.

Authors:  Claudia Wrzesinski; Chrystal M Paulos; Luca Gattinoni; Douglas C Palmer; Andrew Kaiser; Zhiya Yu; Steven A Rosenberg; Nicholas P Restifo
Journal:  J Clin Invest       Date:  2007-02       Impact factor: 14.808

Review 5.  Clinical strategies to enhance T cell reconstitution.

Authors:  Gabrielle L Goldberg; Johannes L Zakrzewski; Miguel A Perales; Marcel R M van den Brink
Journal:  Semin Immunol       Date:  2007-10-26       Impact factor: 11.130

Review 6.  Thymic rejuvenation and aging.

Authors:  Melissa S Ventevogel; Gregory D Sempowski
Journal:  Curr Opin Immunol       Date:  2013-07-04       Impact factor: 7.486

7.  WNT signaling suppression in the senescent human thymus.

Authors:  Sara Ferrando-Martínez; Ezequiel Ruiz-Mateos; Jarrod A Dudakov; Enrico Velardi; Johannes Grillari; David P Kreil; M Ángeles Muñoz-Fernandez; Marcel R M van den Brink; Manuel Leal
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2014-03-22       Impact factor: 6.053

Review 8.  Causes, consequences, and reversal of immune system aging.

Authors:  Encarnacion Montecino-Rodriguez; Beata Berent-Maoz; Kenneth Dorshkind
Journal:  J Clin Invest       Date:  2013-03-01       Impact factor: 14.808

Review 9.  Rejuvenation of the aging T cell compartment.

Authors:  Amanda M Holland; Marcel R M van den Brink
Journal:  Curr Opin Immunol       Date:  2009-07-14       Impact factor: 7.486

10.  Growth hormone mitigates against lethal irradiation and enhances hematologic and immune recovery in mice and nonhuman primates.

Authors:  Benny J Chen; Divino Deoliveira; Ivan Spasojevic; Gregory D Sempowski; Chen Jiang; Kouros Owzar; Xiaojuan Wang; Diane Gesty-Palmer; J Mark Cline; J Daniel Bourland; Greg Dugan; Sarah K Meadows; Pamela Daher; Garrett Muramoto; John P Chute; Nelson J Chao
Journal:  PLoS One       Date:  2010-06-16       Impact factor: 3.240
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