M Gupta1, P Puri, I G Rennie. 1. Department of Ophthalmology, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK.
Abstract
AIM: To present the results of 27 patients who had enucleation for malignant melanoma of the choroid with hydroxyapatite implant wrapped in bovine pericardium. METHOD: A retrospective study was performed on 27 patients, 12 males and 15 females, who had enucleation as a primary treatment for their choroidal melanomas. The patients were followed up at 1 week, 1 month, 3 months, and then every 6 months. A conformer was fitted at 1 week and an artificial eye at 1 month. The average follow up was 1.7 years. RESULTS: No patient had extrusion of the implant. One patient needed repair of the wound, two patients required a lateral tarsal strip, and one patient developed a conjunctival granuloma, which did not need excision. In one patient there was shallowing of the inferior fornix. The cosmetic results and ocular movement were satisfactory in all but one patient. CONCLUSION: Use of bovine pericardium as wrapping material for the hydroxyapatite implants has shown promising results with minimal extrusion rates providing an effective alternative for sclera, eliminating the potential risks of CJD.
AIM: To present the results of 27 patients who had enucleation for malignant melanoma of the choroid with hydroxyapatite implant wrapped in bovine pericardium. METHOD: A retrospective study was performed on 27 patients, 12 males and 15 females, who had enucleation as a primary treatment for their choroidal melanomas. The patients were followed up at 1 week, 1 month, 3 months, and then every 6 months. A conformer was fitted at 1 week and an artificial eye at 1 month. The average follow up was 1.7 years. RESULTS: No patient had extrusion of the implant. One patient needed repair of the wound, two patients required a lateral tarsal strip, and one patient developed a conjunctival granuloma, which did not need excision. In one patient there was shallowing of the inferior fornix. The cosmetic results and ocular movement were satisfactory in all but one patient. CONCLUSION: Use of bovine pericardium as wrapping material for the hydroxyapatite implants has shown promising results with minimal extrusion rates providing an effective alternative for sclera, eliminating the potential risks of CJD.
Authors: J G Heckmann; C J Lang; F Petruch; A Druschky; C Erb; P Brown; B Neundörfer Journal: J Neurol Neurosurg Psychiatry Date: 1997-09 Impact factor: 10.154
Authors: H D Remulla; P A Rubin; J W Shore; F C Sutula; D J Townsend; J J Woog; K V Jahrling Journal: Ophthalmology Date: 1995-04 Impact factor: 12.079
Authors: D R Jordan; L H Allen; A Ells; S Gilberg; S Brownstein; S Munro; S Grahovac; F Raymond Journal: Ophthalmic Plast Reconstr Surg Date: 1995-06 Impact factor: 1.746
Authors: Vadim Elagin; Daria Kuznetsova; Ekaterina Grebenik; Denis A Zolotov; Leonid Istranov; Tatiana Zharikova; Elena Istranova; Anastasia Polozova; Dmitry Reunov; Alexandr Kurkov; Anatoly Shekhter; Elvira R Gafarova; Victor Asadchikov; Sergey M Borisov; Ruslan I Dmitriev; Elena Zagaynova; Peter Timashev Journal: Front Bioeng Biotechnol Date: 2020-02-19