| Literature DB >> 11864588 |
Abstract
Recent evidence indicates that inhibition of histone acetyltransferases may be a primary cause of cellular pathogenesis in polyglutamine diseases such as Huntington disease; the results raise the possibility that pharmacologic manipulation of protein acetylation levels could be of therapeutic benefit.Entities:
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Year: 2002 PMID： 11864588 DOI： 10.1016/s0960-9822(02)00709-1
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834