Literature DB >> 11832205

Cancer as a complex genetic trait: tumor susceptibility in humans and mouse models.

Allan Balmain1.   

Abstract

Cancer directly affects at least one-third of the human population, but the inherited genetic determinants of cancer risk remain largely unknown. Mouse models of human cancer are helping us to understand this disease as a complex genetic trait and thus to identify the multiple genetic variant alleles involved in pathways that affect individual cancer susceptibility.

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Year:  2002        PMID： 11832205     DOI： 10.1016/s0092-8674(02)00622-0

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  45 in total

1.  Mapping quantitative trait loci using the MCMC procedure in SAS.

Authors:  S Xu; Z Hu
Journal:  Heredity (Edinb)       Date:  2010-06-16       Impact factor: 3.821

Review 2.  Preclinical development of molecular-targeted agents for cancer.

Authors:  Alberto Ocana; Atanasio Pandiella; Lillian L Siu; Ian F Tannock
Journal:  Nat Rev Clin Oncol       Date:  2010-12-07       Impact factor: 66.675

3.  An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model.

Authors:  Karlyne M Reilly; Karl W Broman; Roderick T Bronson; Shirley Tsang; Dagan A Loisel; Emily S Christy; Zhonghe Sun; John Diehl; David J Munroe; Robert G Tuskan
Journal:  Cancer Res       Date:  2006-01-01       Impact factor: 12.701

4.  Genetic background influences loss of heterozygosity patterns in radiation-induced mouse thymic lymphoma.

Authors:  Michael Hang; Yurong Huang; Antoine M Snijders; Jian-Hua Mao
Journal:  J Nat Sci       Date:  2015

5.  Mapping of new skin tumor susceptibility loci by a phenotype-driven congenic approach.

Authors:  Kyoko Fujiwara; Yoshinori Inagaki; Masayoshi Soma; Toshinori Ozaki; Hiroki Nagase
Journal:  Oncol Lett       Date:  2018-09-24       Impact factor: 2.967

Review 6.  Systems genetics analysis of cancer susceptibility: from mouse models to humans.

Authors:  David Quigley; Allan Balmain
Journal:  Nat Rev Genet       Date:  2009-07-28       Impact factor: 53.242

Review 7.  Cancer evolution and individual susceptibility.

Authors:  Jesús Pérez-Losada; Andrés Castellanos-Martín; Jian-Hua Mao
Journal:  Integr Biol (Camb)       Date:  2011-01-24       Impact factor: 2.192

Review 8.  Epithelial stem cells, wound healing and cancer.

Authors:  Esther N Arwert; Esther Hoste; Fiona M Watt
Journal:  Nat Rev Cancer       Date:  2012-02-24       Impact factor: 60.716

Review 9.  Missing heritability of complex diseases: Enlightenment by genetic variants from intermediate phenotypes.

Authors:  Adrián Blanco-Gómez; Sonia Castillo-Lluva; María Del Mar Sáez-Freire; Lourdes Hontecillas-Prieto; Jian Hua Mao; Andrés Castellanos-Martín; Jesus Pérez-Losada
Journal:  Bioessays       Date:  2016-05-31       Impact factor: 4.345

10.  Dissociation of epithelial and neuroendocrine carcinoma lineages in the transgenic adenocarcinoma of mouse prostate model of prostate cancer.

Authors:  Teresa Chiaverotti; Suzana S Couto; Annemarie Donjacour; Jian-Hua Mao; Hiroki Nagase; Robert D Cardiff; Gerald R Cunha; Allan Balmain
Journal:  Am J Pathol       Date:  2007-12-21       Impact factor: 4.307
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