Literature DB >> 22362215

Epithelial stem cells, wound healing and cancer.

Esther N Arwert1, Esther Hoste, Fiona M Watt.   

Abstract

It is well established that tissue repair depends on stem cells and that chronic wounds predispose to tumour formation. However, the association between stem cells, wound healing and cancer is poorly understood. Lineage tracing has now shown how stem cells are mobilized to repair skin wounds and how they contribute to skin tumour development. The signalling pathways, including WNT and Hedgehog, that control stem cell behaviour during wound healing are also implicated in tumour formation. Furthermore, tumorigenesis and wound repair both depend on communication between epithelial cells, mesenchymal cells and bone marrow-derived cells. These studies suggest ways to harness stem cells for wound repair while minimizing cancer risk.

Entities:  

Mesh：

Year:  2012        PMID： 22362215     DOI： 10.1038/nrc3217

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  149 in total

1.  Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1.

Authors:  Carrie A Ambler; Fiona M Watt
Journal:  Development       Date:  2010-11       Impact factor: 6.868

2.  Lhx2 maintains stem cell character in hair follicles.

Authors:  Horace Rhee; Lisa Polak; Elaine Fuchs
Journal:  Science       Date:  2006-06-30       Impact factor: 47.728

3.  Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin.

Authors:  Hugo J Snippert; Andrea Haegebarth; Maria Kasper; Viljar Jaks; Johan H van Es; Nick Barker; Marc van de Wetering; Maaike van den Born; Harry Begthel; Robert G Vries; Daniel E Stange; Rune Toftgård; Hans Clevers
Journal:  Science       Date:  2010-03-12       Impact factor: 47.728

4.  The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development.

Authors:  M Sibilia; A Fleischmann; A Behrens; L Stingl; J Carroll; F M Watt; J Schlessinger; E F Wagner
Journal:  Cell       Date:  2000-07-21       Impact factor: 41.582

5.  Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours.

Authors:  Cristina Lo Celso; David M Prowse; Fiona M Watt
Journal:  Development       Date:  2004-04       Impact factor: 6.868

6.  Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin.

Authors:  Alexis Dumortier; André-Dante Durham; Matteo Di Piazza; Sophie Vauclair; Ute Koch; Gisèle Ferrand; Isabel Ferrero; Shadmehr Demehri; Lynda Li Song; Andrew G Farr; Warren J Leonard; Raphael Kopan; Lucio Miele; Daniel Hohl; Daniela Finke; Freddy Radtke
Journal:  PLoS One       Date:  2010-02-18       Impact factor: 3.240

7.  Essential role for Sonic hedgehog during hair follicle morphogenesis.

Authors:  C Chiang; R Z Swan; M Grachtchouk; M Bolinger; Y Litingtung; E K Robertson; M K Cooper; W Gaffield; H Westphal; P A Beachy; A A Dlugosz
Journal:  Dev Biol       Date:  1999-01-01       Impact factor: 3.582

8.  Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome.

Authors:  H Hahn; C Wicking; P G Zaphiropoulous; M R Gailani; S Shanley; A Chidambaram; I Vorechovsky; E Holmberg; A B Unden; S Gillies; K Negus; I Smyth; C Pressman; D J Leffell; B Gerrard; A M Goldstein; M Dean; R Toftgard; G Chenevix-Trench; B Wainwright; A E Bale
Journal:  Cell       Date:  1996-06-14       Impact factor: 41.582

9.  CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer.

Authors:  Dingzhi Wang; Haibin Wang; Joanne Brown; Takiko Daikoku; Wei Ning; Qiong Shi; Ann Richmond; Robert Strieter; Sudhansu K Dey; Raymond N DuBois
Journal:  J Exp Med       Date:  2006-03-27       Impact factor: 14.307

10.  Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.

Authors:  Howard Y Chang; Julie B Sneddon; Ash A Alizadeh; Ruchira Sood; Rob B West; Kelli Montgomery; Jen-Tsan Chi; Matt van de Rijn; David Botstein; Patrick O Brown
Journal:  PLoS Biol       Date:  2004-01-13       Impact factor: 8.029
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  189 in total

1.  Epithelial stem cell mutations that promote squamous cell carcinoma metastasis.

Authors:  Ruth A White; Jill M Neiman; Anand Reddi; Gangwen Han; Stanca Birlea; Doyel Mitra; Laikuan Dionne; Pam Fernandez; Kazutoshi Murao; Li Bian; Stephen B Keysar; Nathaniel B Goldstein; Ningjing Song; Sophia Bornstein; Zheyi Han; Xian Lu; Joshua Wisell; Fulun Li; John Song; Shi-Long Lu; Antonio Jimeno; Dennis R Roop; Xiao-Jing Wang
Journal:  J Clin Invest       Date:  2013-09-03       Impact factor: 14.808

2.  Potentiating vascular-targeted photodynamic therapy through CSF-1R modulation of myeloid cells in a preclinical model of prostate cancer.

Authors:  Souhil Lebdai; Mathieu Gigoux; Ricardo Alvim; Alexander Somma; Karan Nagar; Abdel Rahmene Azzouzi; Olivier Cussenot; Taha Merghoub; Jedd D Wolchok; Avigdor Scherz; Kwanghee Kim; Jonathan Coleman
Journal:  Oncoimmunology       Date:  2019-03-28       Impact factor: 8.110

3.  An FGFR inhibitor converts the tumor promoting effect of TGF-β by the induction of fibroblast-associated genes of hepatoma cells.

Authors:  H-R Zhang; X-D Wang; X Yang; D Chen; J Hao; R Cao; X-Z Wu
Journal:  Oncogene       Date:  2017-03-06       Impact factor: 9.867

Review 4.  Cells of origin of pancreatic neoplasms.

Authors:  Junpei Yamaguchi; Yukihiro Yokoyama; Toshio Kokuryo; Tomoki Ebata; Masato Nagino
Journal:  Surg Today       Date:  2017-03-04       Impact factor: 2.549

Review 5.  Tracking cells in their native habitat: lineage tracing in epithelial neoplasia.

Authors:  Maria P Alcolea; Philip H Jones
Journal:  Nat Rev Cancer       Date:  2013-02-07       Impact factor: 60.716

Review 6.  Epithelial stem cells in adult skin.

Authors:  Ana Mafalda Baptista Tadeu; Valerie Horsley
Journal:  Curr Top Dev Biol       Date:  2014       Impact factor: 4.897

7.  Stem Cell Lineage Infidelity Drives Wound Repair and Cancer.

Authors:  Yejing Ge; Nicholas C Gomez; Rene C Adam; Maria Nikolova; Hanseul Yang; Akanksha Verma; Catherine Pei-Ju Lu; Lisa Polak; Shaopeng Yuan; Olivier Elemento; Elaine Fuchs
Journal:  Cell       Date:  2017-04-20       Impact factor: 41.582

8.  IL-33 activates tumor stroma to promote intestinal polyposis.

Authors:  Rebecca L Maywald; Stephanie K Doerner; Luca Pastorelli; Carlo De Salvo; Susan M Benton; Emily P Dawson; Denise G Lanza; Nathan A Berger; Sanford D Markowitz; Heinz-Josef Lenz; Joseph H Nadeau; Theresa T Pizarro; Jason D Heaney
Journal:  Proc Natl Acad Sci U S A       Date:  2015-04-27       Impact factor: 11.205

9.  Magnetic resonance perfusion and diffusion characteristics of granulomatous diseases mimic those of malignant lesions: six case reports.

Authors:  Misa Sumi; Yukinori Takagi; Miho Sasaki; Sato Eida; Ikuo Katayama; Yuka Hotokezaka; Takashi Nakamura
Journal:  Oral Radiol       Date:  2017-03-16       Impact factor: 1.852

10.  The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas.

Authors:  Daniela F Quail; Robert L Bowman; Leila Akkari; Marsha L Quick; Alberto J Schuhmacher; Jason T Huse; Eric C Holland; James C Sutton; Johanna A Joyce
Journal:  Science       Date:  2016-05-20       Impact factor: 47.728
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