Literature DB >> 11797953

A Monte Carlo study of radiation transport through multileaf collimators.

J O Kim1, J V Siebers, P J Keall, M R Arnfield, R Mohan.   

Abstract

Due to the significant increase in the number of monitor units used to deliver a dynamic IMRT treatment, the total MLC leakage (transmission plus scatter) can exceed 10% of the maximum in-field dose. To avoid dosimetric errors, this leakage must be accurately accounted for in the dose calculation and conversion of optimized intensity patterns to MLC trajectories used for treatment delivery. In this study, we characterized the leaf end transmission and leakage radiation for Varian 80- and 120-leaf MLCs using Monte Carlo simulations. The complex geometry of the MLC, including the rounded leaf end, leaf edges (tongue-and-groove and offset notch), mounting slots, and holes was modeled using MCNP4b. Studies were undertaken to determine the leakage as a function of field size, components of the leakage, electron contamination, beam hardening and leaf tip effects. The leakage radiation with the MLC configured to fully block the field was determined. Dose for 6 and 18 MV beams was calculated at 5 cm depth in a water phantom located at 95 cm SSD, and normalized to the dose for an open field. Dose components were scored separately for radiation transmitted through and scattered from the MLC. For the 80-leaf MLC at 6 MV, the average leakage dose is 1.6%, 1.7%, 1.8%, and 1.9% for 5 x 5, 10 x 10, 15 x 15, and 20 x 20cm2 fields, respectively. For the 120-leaf MLC at 6 MV, the average leakage dose is 1.6%, 1.6%, 1.7%, and 1.9% for the same field sizes. Measured leakage values for the 120-leaf MLC agreed with calculated values to within 0.1% of the open field dose. The increased leakage with field size is attributed to MLC scattered radiation. The fractional electron contamination for a blocked MLC field is greater than that for an open field. The MLC attenuation significantly affects the photon spectrum, resulting in an increase in percent depth dose at 6 MV, however, little effect is observed at 18 MV. Both phantom scatter and the finite source size contribute to the leaf tip profile observed in phantom. The results of this paper can be applied to fluence-to-trajectory and trajectory-to-fluence calculations for IMRT.

Entities:  

Mesh:

Substances:

Year:  2001        PMID: 11797953     DOI: 10.1118/1.1420734

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  14 in total

1.  Analytic IMRT dose calculations utilizing Monte Carlo to predict MLC fluence modulation.

Authors:  I B Mihaylov; F A Lerma; Y Wu; J V Siebers
Journal:  Med Phys       Date:  2006-04       Impact factor: 4.071

2.  Monte Carlo-based adaptive EPID dose kernel accounting for different field size responses of imagers.

Authors:  Song Wang; Joseph K Gardner; John J Gordon; Weidong Li; Luke Clews; Peter B Greer; Jeffrey V Siebers
Journal:  Med Phys       Date:  2009-08       Impact factor: 4.071

3.  The Influence of Acquisition Mode on the Dosimetric Performance of an Amorphous Silicon Electronic Portal Imaging Device.

Authors:  Omemh Bawazeer; Sisira Herath; Siva Sarasanandarajah; Tomas Kron; Pradip Deb
Journal:  J Med Phys       Date:  2017 Apr-Jun

4.  Three-dimensional gamma analysis of dose distributions in individual structures for IMRT dose verification.

Authors:  Yuuki Tomiyama; Fujio Araki; Takeshi Oono; Kazunari Hioki
Journal:  Radiol Phys Technol       Date:  2014-05-06

Review 5.  Monte Carlo methods for device simulations in radiation therapy.

Authors:  Hyojun Park; Harald Paganetti; Jan Schuemann; Xun Jia; Chul Hee Min
Journal:  Phys Med Biol       Date:  2021-09-14       Impact factor: 4.174

6.  Development and validation of MCNPX-based Monte Carlo treatment plan verification system.

Authors:  Iraj Jabbari; Shahram Monadi
Journal:  J Med Phys       Date:  2015 Apr-Jun

7.  aSi-EPID transit signal calibration for dynamic beams: a needful step for the IMRT in vivo dosimetry.

Authors:  Francesca Greco; Angelo Piermattei; Luigi Azario; Lorenzo Placidi; Savino Cilla; Rocchina Caivano; Vincenzo Fusco; Andrea Fidanzio
Journal:  Med Biol Eng Comput       Date:  2013-07-09       Impact factor: 2.602

8.  Performance Evaluation of Algorithms in Lung IMRT: A comparison of Monte Carlo, Pencil Beam, Superposition, Fast Superposition and Convolution Algorithms.

Authors:  T Verma; N K Painuly; S P Mishra; M Shajahan; N Singh; M L B Bhatt; N Jamal; M C Pant
Journal:  J Biomed Phys Eng       Date:  2016-09-01

9.  Evaluation of the radiobiological gamma index with motion interplay in tangential IMRT breast treatment.

Authors:  Iori Sumida; Hajime Yamaguchi; Indra J Das; Hisao Kizaki; Keiko Aboshi; Mari Tsujii; Yuji Yamada; Kiesuke Tamari; Osamu Suzuki; Yuji Seo; Fumiaki Isohashi; Yasuo Yoshioka; Kazuhiko Ogawa
Journal:  J Radiat Res       Date:  2016-08-16       Impact factor: 2.724

10.  Monte Carlo dose verification of prostate patients treated with simultaneous integrated boost intensity modulated radiation therapy.

Authors:  Nesrin Dogan; Ivaylo Mihaylov; Yan Wu; Paul J Keall; Jeffrey V Siebers; Michael P Hagan
Journal:  Radiat Oncol       Date:  2009-06-15       Impact factor: 3.481

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.