Literature DB >> 11767459

[Interleukin-1beta and depressive states].

O E Zubareva1, O M Efremov, A S Simbirtsev, V M Klimenko.   

Abstract

Administration of Interleukin-1 beta (IL-1 beta) in pyrogenic and subpyrogenic doses induced a depression of social and exploratory behaviour in rats. A reduction in locomotor activity only occurred with pyrogenic doses of the IL-1 beta. The low dose induced the reduction whereas the high dose the increase of anxiety in elevated plus maze. The opposite effects of two doses of IL-1 beta were observed also in a test with saccharine.

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Year:  2001        PMID： 11767459

Source DB:  PubMed          Journal:  Ross Fiziol Zh Im I M Sechenova        ISSN： 0869-8139


  5 in total

1.  The effects of proinflammatory cytokines on the formation of behavior in early postnatal ontogenesis.

Authors:  O E Zubareva; A P Eliseeva; A S Simbirtsev; V M Klimenko
Journal:  Neurosci Behav Physiol       Date:  2006-05

2.  The psychomodulatory action of subpyrogenic doses of interleukin-1beta in conditions of chronic administration to rats.

Authors:  E S Sokolova; V I Lyudyno; A S Simbirtsev; V M Klimenko
Journal:  Neurosci Behav Physiol       Date:  2007-06

3.  Long-term disorders of behavior in rats induced by administration of tumor necrosis factor during early postnatal ontogenesis.

Authors:  O E Zubareva; V M Klimenko
Journal:  Neurosci Behav Physiol       Date:  2008-12-17

4.  Impairment of exploratory behavior and spatial memory in adolescent rats in lithium-pilocarpine model of temporal lobe epilepsy.

Authors:  S V Kalemenev; O E Zubareva; E V Frolova; V V Sizov; V V Lavrentyeva; N Ya Lukomskaya; K Kh Kim; A V Zaitsev; L G Magazanik
Journal:  Dokl Biol Sci       Date:  2015-09-03

5.  Effects of interleukin-1beta and lipopolysaccharide on behavior of mice in the elevated plus-maze and open field tests.

Authors:  Artur H Swiergiel; Adrian J Dunn
Journal:  Pharmacol Biochem Behav       Date:  2007-02-16       Impact factor: 3.533
  5 in total

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