Literature DB >> 11762661

Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis.

A P Kenyon1, C N Piercy, J Girling, C Williamson, R M Tribe, A H Shennan.   

Abstract

Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any abnormality in liver function tests (including total serum bile acids) and discuss the implications of this for clinical practice.

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Year:  2001        PMID: 11762661     DOI: 10.1111/j.1471-0528.2003.00281.x

Source DB:  PubMed          Journal:  BJOG        ISSN: 1470-0328            Impact factor:   6.531


  13 in total

Review 1.  Intrahepatic cholestasis of pregnancy.

Authors:  Victoria Geenes; Catherine Williamson
Journal:  World J Gastroenterol       Date:  2009-05-07       Impact factor: 5.742

2.  Pruritus in pregnancy: a study of anatomical distribution and prevalence in relation to the development of obstetric cholestasis.

Authors:  A P Kenyon; R M Tribe; C Nelson-Piercy; J C Girling; C Williamson; P T Seed; S Vaughan-Jones; A H Shennan
Journal:  Obstet Med       Date:  2010-03-04

3.  Intrahepatic Cholestasis of Pregnancy.

Authors:  Frank Lammert; Hanns-Ulrich Marschall; Siegfried Matern
Journal:  Curr Treat Options Gastroenterol       Date:  2003-04

Review 4.  Interventions for treating cholestasis in pregnancy.

Authors:  Vinita Gurung; Philippa Middleton; Stephen J Milan; William Hague; Jim G Thornton
Journal:  Cochrane Database Syst Rev       Date:  2013-06-24

5.  The biochemical diagnosis of intrahepatic cholestasis of pregnancy.

Authors:  Adam Morton; Josephine Laurie
Journal:  Obstet Med       Date:  2018-11-04

6.  Total serum bile acids or serum bile acid profile, or both, for the diagnosis of intrahepatic cholestasis of pregnancy.

Authors:  Cristina Manzotti; Giovanni Casazza; Tea Stimac; Dimitrinka Nikolova; Christian Gluud
Journal:  Cochrane Database Syst Rev       Date:  2019-07-05

7.  Pharmacological interventions for treating intrahepatic cholestasis of pregnancy.

Authors:  Kate F Walker; Lucy C Chappell; William M Hague; Philippa Middleton; Jim G Thornton
Journal:  Cochrane Database Syst Rev       Date:  2020-07-27

8.  Intrahepatic cholestasis of pregnancy: Relationship between bile acid levels and maternal and fetal complications.

Authors:  Bilge Çetinkaya Demir; Esra Şahin Güneş; Mehmet Aral Atalay
Journal:  Turk J Obstet Gynecol       Date:  2014-09-15

9.  Can we predict severity of intrahepatic cholestasis of pregnancy using inflammatory markers?

Authors:  Çiğdem Yayla Abide; Fisun Vural; Çetin Kılıççı; Evrim Bostancı Ergen; İlter Yenidede; Ahmet Eser; Oya Pekin
Journal:  Turk J Obstet Gynecol       Date:  2017-09-30

10.  The prevalence and pregnancy outcomes of intrahepatic cholestasis of pregnancy: A retrospective clinical audit review.

Authors:  Fergus W Gardiner; Ruth McCuaig; Chris Arthur; Thomas Carins; Adam Morton; Josephine Laurie; Teresa Neeman; Boon Lim; Michael J Peek
Journal:  Obstet Med       Date:  2018-10-25
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