Literature DB >> 11733770

Network dynamics and cell physiology.

J J Tyson1, K Chen, B Novak.   

Abstract

Complex assemblies of interacting proteins carry out most of the interesting jobs in a cell, such as metabolism, DNA synthesis, movement and information processing. These physiological properties play out as a subtle molecular dance, choreographed by underlying regulatory networks. To understand this dance, a new breed of theoretical molecular biologists reproduces these networks in computers and in the mathematical language of dynamical systems.

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Year:  2001        PMID: 11733770     DOI: 10.1038/35103078

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN: 1471-0072            Impact factor:   94.444


  133 in total

1.  Dynamics of the cell cycle: checkpoints, sizers, and timers.

Authors:  Zhilin Qu; W Robb MacLellan; James N Weiss
Journal:  Biophys J       Date:  2003-12       Impact factor: 4.033

2.  Integrative analysis of cell cycle control in budding yeast.

Authors:  Katherine C Chen; Laurence Calzone; Attila Csikasz-Nagy; Frederick R Cross; Bela Novak; John J Tyson
Journal:  Mol Biol Cell       Date:  2004-05-28       Impact factor: 4.138

3.  The yeast cell-cycle network is robustly designed.

Authors:  Fangting Li; Tao Long; Ying Lu; Qi Ouyang; Chao Tang
Journal:  Proc Natl Acad Sci U S A       Date:  2004-03-22       Impact factor: 11.205

4.  Bridging the gap between stochastic and deterministic regimes in the kinetic simulations of the biochemical reaction networks.

Authors:  Jacek Puchałka; Andrzej M Kierzek
Journal:  Biophys J       Date:  2004-03       Impact factor: 4.033

Review 5.  Software for systems biology: from tools to integrated platforms.

Authors:  Samik Ghosh; Yukiko Matsuoka; Yoshiyuki Asai; Kun-Yi Hsin; Hiroaki Kitano
Journal:  Nat Rev Genet       Date:  2011-11-03       Impact factor: 53.242

6.  A nonlinear dynamical theory of cell injury.

Authors:  Donald J DeGracia; Zhi-Feng Huang; Sui Huang
Journal:  J Cereb Blood Flow Metab       Date:  2012-03-07       Impact factor: 6.200

7.  Emergent bistability: effects of additive and multiplicative noise.

Authors:  S Ghosh; S Banerjee; I Bose
Journal:  Eur Phys J E Soft Matter       Date:  2012-02-23       Impact factor: 1.890

Review 8.  Toward the virtual cell: automated approaches to building models of subcellular organization "learned" from microscopy images.

Authors:  Taráz E Buck; Jieyue Li; Gustavo K Rohde; Robert F Murphy
Journal:  Bioessays       Date:  2012-07-10       Impact factor: 4.345

9.  Computational modeling of signaling pathways mediating cell cycle checkpoint control and apoptotic responses to ionizing radiation-induced DNA damage.

Authors:  Yuchao Zhao; In Chio Lou; Rory B Conolly
Journal:  Dose Response       Date:  2011-10-25       Impact factor: 2.658

10.  Process-based network decomposition reveals backbone motif structure.

Authors:  Guanyu Wang; Chenghang Du; Hao Chen; Rahul Simha; Yongwu Rong; Yi Xiao; Chen Zeng
Journal:  Proc Natl Acad Sci U S A       Date:  2010-05-24       Impact factor: 11.205

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