Literature DB >> 11719181

When the message goes awry: disease-producing mutations that influence mRNA content and performance.

J T Mendell1, H C Dietz.   

Abstract

Mutations that cause disease commonly occur in the coding sequence and directly influence protein structure and function. However, many diseases result from mutations that influence various aspects of mRNA metabolism, including processing, export, stability, and translational control.

Mesh：

Substances：

Year:  2001        PMID： 11719181     DOI： 10.1016/s0092-8674(01)00583-9

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  105 in total

1.  HLA-G allelic variants are associated with differences in the HLA-G mRNA isoform profile and HLA-G mRNA levels.

Authors:  Thomas Vauvert F Hviid; Sine Hylenius; Christina Rørbye; Lone G Nielsen
Journal:  Immunogenetics       Date:  2003-04-24       Impact factor: 2.846

2.  Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.

Authors:  Nelson B Olivier; Roger B Altman; Jonas Noeske; Gregory S Basarab; Erin Code; Andrew D Ferguson; Ning Gao; Jian Huang; Manuel F Juette; Stephania Livchak; Matthew D Miller; D Bryan Prince; Jamie H D Cate; Ed T Buurman; Scott C Blanchard
Journal:  Proc Natl Acad Sci U S A       Date:  2014-11-03       Impact factor: 11.205

Review 3.  The roles of TTP and BRF proteins in regulated mRNA decay.

Authors:  Sandhya Sanduja; Fernando F Blanco; Dan A Dixon
Journal:  Wiley Interdiscip Rev RNA       Date:  2011 Jan-Feb       Impact factor: 9.957

4.  Conserved sequence elements associated with exon skipping.

Authors:  Elana Miriami; Hanah Margalit; Ruth Sperling
Journal:  Nucleic Acids Res       Date:  2003-04-01       Impact factor: 16.971

Review 5.  Nuclear translation: what is the evidence?

Authors:  James E Dahlberg; Elsebet Lund; Elizabeth B Goodwin
Journal:  RNA       Date:  2003-01       Impact factor: 4.942

6.  Rapid deadenylation triggered by a nonsense codon precedes decay of the RNA body in a mammalian cytoplasmic nonsense-mediated decay pathway.

Authors:  Chyi-Ying A Chen; Ann-Bin Shyu
Journal:  Mol Cell Biol       Date:  2003-07       Impact factor: 4.272

Review 7.  The ribosome filter hypothesis.

Authors:  Vincent P Mauro; Gerald M Edelman
Journal:  Proc Natl Acad Sci U S A       Date:  2002-09-09       Impact factor: 11.205

8.  Efficient downregulation of immunoglobulin mu mRNA with premature translation-termination codons requires the 5'-half of the VDJ exon.

Authors:  Marc Bühler; Alexandra Paillusson; Oliver Mühlemann
Journal:  Nucleic Acids Res       Date:  2004-06-21       Impact factor: 16.971

9.  Natural selection affects frequencies of AG and GT dinucleotides at the 5' and 3' ends of exons.

Authors:  S T Eskesen; F N Eskesen; A Ruvinsky
Journal:  Genetics       Date:  2004-05       Impact factor: 4.562

10.  Detection of allelic imbalance in the gene expression of hMSH2 or RB1 in lymphocytes from pedigrees of hereditary, nonpolyposis, colorectal cancer and retinoblastoma by an RNA difference plot.

Authors:  Yoshinori Murakami; Kana Isogai; Hiroyuki Tomita; Mika Sakurai-Yageta; Tomoko Maruyama; Akio Hidaka; Kiyoshi Nose; Kokichi Sugano; Akihiro Kaneko
Journal:  J Hum Genet       Date:  2004-10-08       Impact factor: 3.172
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