Literature DB >> 11700578

Antifungal activity against Candida species of the selective serotonin-reuptake inhibitor, sertraline.

C Lass-Flörl1, M P Dierich, D Fuchs, E Semenitz, M Ledochowski.   

Abstract

Three patients with premenstrual dysphoric disorder (PMDD) and recurrent vulvovaginal candidiasis (VVC) underwent sertraline therapy (Tresleen, a selective serotonin-reuptake inhibitor; Pfizer) for PMDD. During sertraline intervention, patients had no recurrent episodes of acute VVC. Antifungal activity was observed for sertraline against various isolates of Candida species.

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Year:  2001        PMID: 11700578     DOI: 10.1086/324589

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  19 in total

1.  The antidepressant sertraline targets intracellular vesiculogenic membranes in yeast.

Authors:  Meredith M Rainey; Daniel Korostyshevsky; Sean Lee; Ethan O Perlstein
Journal:  Genetics       Date:  2010-05-10       Impact factor: 4.562

2.  Relative risk of vaginal candidiasis after use of antibiotics compared with antidepressants in women.

Authors:  Richard Elliott
Journal:  Drug Saf       Date:  2005       Impact factor: 5.606

3.  Anti-Candida activity of fluoxetine alone and combined with fluconazole: a synergistic action against fluconazole-resistant strains.

Authors:  Ana S Oliveira; Carlos A Gaspar; Rita Palmeira-de-Oliveira; José Martinez-de-Oliveira; Ana Palmeira-de-Oliveira
Journal:  Antimicrob Agents Chemother       Date:  2014-05-05       Impact factor: 5.191

Review 4.  Antifungal adjuvants: Preserving and extending the antifungal arsenal.

Authors:  Arielle Butts; Glen E Palmer; P David Rogers
Journal:  Virulence       Date:  2016-07-26       Impact factor: 5.882

5.  Anti-Candida activity of antidepressants sertraline and fluoxetine: effect upon pre-formed biofilms.

Authors:  Ana S Oliveira; José Martinez-de-Oliveira; Gilbert G G Donders; Rita Palmeira-de-Oliveira; Ana Palmeira-de-Oliveira
Journal:  Med Microbiol Immunol       Date:  2018-03-19       Impact factor: 3.402

6.  The antidepressant sertraline provides a promising therapeutic option for neurotropic cryptococcal infections.

Authors:  Bing Zhai; Cheng Wu; Linqi Wang; Matthew S Sachs; Xiaorong Lin
Journal:  Antimicrob Agents Chemother       Date:  2012-04-16       Impact factor: 5.191

7.  Effects of psychological stress and fluoxetine on development of oral candidiasis in rats.

Authors:  María J Núñez; Silvia Novío; Juan Antonio Suárez; José Balboa; Manuel Freire-Garabal
Journal:  Clin Vaccine Immunol       Date:  2010-02-03

8.  The Synergistic Effect of Azoles and Fluoxetine against Resistant Candida albicans Strains Is Attributed to Attenuating Fungal Virulence.

Authors:  Wenrui Gu; Dongmei Guo; Liuping Zhang; Dongmei Xu; Shujuan Sun
Journal:  Antimicrob Agents Chemother       Date:  2016-09-23       Impact factor: 5.191

9.  In vitro synergistic effects of chlorpromazine and sertraline in combination with amphotericin B against Cryptococcus neoformans var. grubii.

Authors:  Luana Rossato; Érico S Loreto; Régis A Zanette; Francieli Chassot; Janio M Santurio; Sydney H Alves
Journal:  Folia Microbiol (Praha)       Date:  2016-02-04       Impact factor: 2.099

Review 10.  Drug repurposing for antimicrobial discovery.

Authors:  Maya A Farha; Eric D Brown
Journal:  Nat Microbiol       Date:  2019-03-04       Impact factor: 17.745

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