Literature DB >> 11689530

Seasonal variation in cause-specific mortality: are there high-risk groups? 25-year follow-up of civil servants from the first Whitehall study.

C T van Rossum1, M J Shipley, H Hemingway, D E Grobbee, J P Mackenbach, M G Marmot.   

Abstract

OBJECTIVES: To determine the seasonal effect on all-cause and cause-specific mortality and to identify high-risk groups.
METHODS: A 25-year follow-up of 19,019 male civil servants aged 40-69 years.
RESULTS: All-cause mortality was seasonal (ratio of highest mortality rate during winter versus lowest rate during summer 1.22, 95% CI : 1.1-1.3), largely due to the seasonal nature of ischaemic heart disease. Participants at high risk based on age, employment grade, blood pressure, cholesterol, forced expiratory volume, smoking and diabetes did not have higher seasonal mortality, although participants with ischaemic heart disease at baseline did have a higher seasonality effect (1.38, 95% CI : 1.2-1.6) than those without (1.18, 95% CI : 1.1-1.3) (P = 0.03).
CONCLUSIONS: Seasonal mortality differences were greater among those with prevalent ischaemic heart disease and at older ages, but were not greater in individuals of lower socioeconomic status or with a high multivariate risk score. Since seasonal differences showed no evidence of declining over time, elucidating their causes and preventive strategies remains a public health challenge.

Entities:  

Mesh:

Year:  2001        PMID: 11689530     DOI: 10.1093/ije/30.5.1109

Source DB:  PubMed          Journal:  Int J Epidemiol        ISSN: 0300-5771            Impact factor:   7.196


  28 in total

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8.  Vulnerability to winter mortality in elderly people in Britain: population based study.

Authors:  Paul Wilkinson; Sam Pattenden; Ben Armstrong; Astrid Fletcher; R Sari Kovats; Punam Mangtani; Anthony J McMichael
Journal:  BMJ       Date:  2004-08-17

9.  Seasonal variation in meteorological parameters and office, ambulatory and home blood pressure: predicting factors and clinical implications.

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Authors:  Cees van den Wijngaard; Liselotte van Asten; Wilfrid van Pelt; Nico J D Nagelkerke; Robert Verheij; Albert J de Neeling; Arnold Dekkers; Marianne A B van der Sande; Hans van Vliet; Marion P G Koopmans
Journal:  Emerg Infect Dis       Date:  2008-06       Impact factor: 6.883

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