| Literature DB >> 11683712 |
L Ramunno1, G Cosenza, M Pappalardo, E Longobardi, D Gallo, N Pastore, P Di Gregorio, A Rando.
Abstract
Two novel alleles at the goat CSN1S2 locus have been identified: CSN1S2(F) and CSN1S2(D). Sequence analyses revealed that the CSN1S2(F) allele is characterized by a G --> A transition at the 13th nucleotide in exon 3 changing the seventh amino acid of the mature protein from Val to Ile. The CSN1S2(D) allele, apparently associated with a decreased synthesis of alpha s2-casein, is characterized by a 106-bp deletion, involving the last 11 bp of the exon 11 and the first 95 bp of the following intron. Methods (PCR-RFLP and PCR) for identification of carriers of these alleles have been developed.Entities:
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Year: 2001 PMID： 11683712 DOI： 10.1046/j.1365-2052.2001.00786.x
Source DB: PubMed Journal: Anim Genet ISSN： 0268-9146 Impact factor: 3.169