| Literature DB >> 11683384 |
Abstract
ATP-dependent chromatin-remodeling machines of the SWI/SNF family are involved in many cellular processes in eukaryotic nuclei, such as transcription, replication, repair and recombination. Remodeling factors driven by the ATPase ISWI make up a subgroup of this family that exhibits defined mechanistic and functional characteristics. ISWI-induced nucleosome mobility endows nucleosomal arrays with dynamic properties and recent results suggest that ISWI-type remodelers have diverse functions that range from transcriptional regulation to chromatin assembly and maintenance of chromosome structure.Entities:
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Year: 2001 PMID: 11683384 DOI: 10.1242/jcs.114.14.2561
Source DB: PubMed Journal: J Cell Sci ISSN: 0021-9533 Impact factor: 5.285