Literature DB >> 11682305

Genome-wide variation in the human and fruitfly: a comparison.

C F Aquadro1, V Bauer DuMont, F A Reed.   

Abstract

Average levels of nucleotide diversity are ten-fold lower in humans than in the fruitfly, Drosophila melanogaster. Despite this difference, apparently as a result of a lower population size, patterns of genomic diversity are strikingly similar in being correlated with local rates of recombination, and influenced by similar interactions between positive natural selection and recombination. Both species also show lower levels of variation on average in non-African compared to African populations, reflecting a similar evolutionary history and perhaps both natural selection and founder effects in new environments.

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Year:  2001        PMID： 11682305     DOI： 10.1016/s0959-437x(00)00245-8

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  46 in total

1.  Interrogating a high-density SNP map for signatures of natural selection.

Authors:  Joshua M Akey; Ge Zhang; Kun Zhang; Li Jin; Mark D Shriver
Journal:  Genome Res       Date:  2002-12       Impact factor: 9.043

2.  Molecular population genetics of the beta-esterase gene cluster of Drosophila melanogaster.

Authors:  Evgeniy S Balakirev; Francisco J Ayala
Journal:  J Genet       Date:  2003-12       Impact factor: 1.166

3.  From DNA to fitness differences: sequences and structures of adaptive variants of Colias phosphoglucose isomerase (PGI).

Authors:  Christopher W Wheat; Ward B Watt; David D Pollock; Patricia M Schulte
Journal:  Mol Biol Evol       Date:  2005-11-16       Impact factor: 16.240

4.  Positive selection can create false hotspots of recombination.

Authors:  Floyd A Reed; Sarah A Tishkoff
Journal:  Genetics       Date:  2005-12-30       Impact factor: 4.562

5.  How reliable are empirical genomic scans for selective sweeps?

Authors:  Kosuke M Teshima; Graham Coop; Molly Przeworski
Journal:  Genome Res       Date:  2006-05-10       Impact factor: 9.043

6.  Effects of population structure and sex on association between serotonin receptors and Drosophila heart rate.

Authors:  Naruo Nikoh; April Duty; Greg Gibson
Journal:  Genetics       Date:  2004-12       Impact factor: 4.562

7.  Evidence for widespread positive and purifying selection across the European rabbit (Oryctolagus cuniculus) genome.

Authors:  Miguel Carneiro; Frank W Albert; José Melo-Ferreira; Nicolas Galtier; Philippe Gayral; Jose A Blanco-Aguiar; Rafael Villafuerte; Michael W Nachman; Nuno Ferrand
Journal:  Mol Biol Evol       Date:  2012-01-31       Impact factor: 16.240

8.  No effect of recombination on the efficacy of natural selection in primates.

Authors:  Kevin Bullaughey; Molly Przeworski; Graham Coop
Journal:  Genome Res       Date:  2008-01-16       Impact factor: 9.043

9.  A genome-wide distribution of 8-oxoguanine correlates with the preferred regions for recombination and single nucleotide polymorphism in the human genome.

Authors:  Mizuki Ohno; Tomofumi Miura; Masato Furuichi; Yohei Tominaga; Daisuke Tsuchimoto; Kunihiko Sakumi; Yusaku Nakabeppu
Journal:  Genome Res       Date:  2006-05       Impact factor: 9.043

10.  Polymorphism patterns in two tightly linked developmental genes, Idgf1 and Idgf3, of Drosophila melanogaster.

Authors:  Martina Zurovcová; Francisco J Ayala
Journal:  Genetics       Date:  2002-09       Impact factor: 4.562
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