Literature DB >> 1167341

Teratogenic effects of diphenylhydantoin.

V Dabee, A G Hart, R M Hurley.   

Abstract

A child aged 24 months had multiple congenital abnormalities and delayed development. The 28-year-old mother had been treated since childhood with anticonvulsants. Her previous pregnancies had resulted in three early spontaneous abortions and one child with severe bilateral cleft lip and palate. This case report further suggests a relationship between maternal diphenylhydantoin use and fetal anomalies.

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Year:  1975        PMID: 1167341      PMCID: PMC1955998     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN: 0008-4409            Impact factor:   8.262


  9 in total

1.  Are anticonvulsants teratogenic?

Authors:  H Pashayan; D Pruzansky; S Qruzansky
Journal:  Lancet       Date:  1971-09-25       Impact factor: 79.321

2.  Anticonvulsant drugs and congenital abnormalities.

Authors:  S R Meadow
Journal:  Lancet       Date:  1968-12-14       Impact factor: 79.321

3.  Ceft palate in the offspring of female mice treated with phenytoin.

Authors:  J Elshove
Journal:  Lancet       Date:  1969-11-15       Impact factor: 79.321

4.  Infants exposed in utero to antiepileptic drugs. A prospective study.

Authors:  R M Hill; W M Verniaud; M G Horning; L B McCulley; N F Morgan
Journal:  Am J Dis Child       Date:  1974-05

5.  Diphenylhydantoin and selected congenital malformations.

Authors:  R R Monson; L Rosenberg; S C Hartz; S Shapiro; O P Heinonen; D Slone
Journal:  N Engl J Med       Date:  1973-11-15       Impact factor: 91.245

6.  Relation of dosage and time of administration of diphenylhydantoin to its teratogenic effect in mice.

Authors:  R D Harbison; B A Becker
Journal:  Teratology       Date:  1969-11

7.  Teratogenic effects of diphenylhydantoin in Swiss-Webster and A-J mice.

Authors:  J E Gibson; B A Becker
Journal:  Proc Soc Exp Biol Med       Date:  1968-07

8.  Effect of phenobarbital and SKF 525A pretreatment on diphenylhydantoin teratogenicity in mice.

Authors:  R D Harbison; B A Becker
Journal:  J Pharmacol Exp Ther       Date:  1970-11       Impact factor: 4.030

9.  Placental transfer and neonatal elimination of diphenylhydantoin.

Authors:  B L Mirkin
Journal:  Am J Obstet Gynecol       Date:  1971-03-15       Impact factor: 8.661

  9 in total
  2 in total

1.  Single-dose antibiotic treatment: a new approach to lower urinary tract infections in primary care.

Authors:  S Shortt
Journal:  Can Fam Physician       Date:  1981-01       Impact factor: 3.275

2.  Maternal anticonvulsants and optic nerve hypoplasia.

Authors:  C S Hoyt; F A Billson
Journal:  Br J Ophthalmol       Date:  1978-01       Impact factor: 4.638

  2 in total

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