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Literature DB >> 415754

Maternal anticonvulsants and optic nerve hypoplasia.

Abstract

Seven patients with optic nerve hypoplasia, born of epileptic mothers, are presented. All the mothers took anticonvulsants during pregnancy. The possibility that maternal anticonvulsant therapy may play a role in the genesis of optic nerve hypoplasia is discussed in the light of what is known about the teratogenicity of these agents.

Entities: Disease Species

Mesh：

Substances：
Phenytoin

Year: 1978 PMID： 415754 PMCID： PMC1043128 DOI： 10.1136/bjo.62.1.3

Source DB: PubMed Journal: Br J Ophthalmol ISSN： 0007-1161 Impact factor: 4.638

14 in total

1. Teratogenic effects of diphenylhydantoin.

Authors: V Dabee; A G Hart; R M Hurley
Journal: Can Med Assoc J Date: 1975-01-11 Impact factor: 8.262

2. On bilateral aplasia of the optic nerve.

Authors: J KYTILA; P MIETTINEN
Journal: Acta Ophthalmol (Copenh) Date: 1961

3. Maternal epilepsy and abnormalities of the fetus and newborn.

Authors: B D Speidel; S R Meadow
Journal: Lancet Date: 1972-10-21 Impact factor: 79.321

4. Optic hypoplasia and hypopituitarism.

Authors: F Billson; I J Hopkins
Journal: Lancet Date: 1972-04-22 Impact factor: 79.321

5. Anticonvulsant drugs and congenital abnormalities.

Authors: S R Meadow
Journal: Lancet Date: 1968-12-14 Impact factor: 79.321

6. Development of the bovine eye.

Authors: S I Bistner; L Rubin; G Aguirre
Journal: Am J Vet Res Date: 1973-01 Impact factor: 1.156

7. Optic nerve hypoplasia. A report of 20 cases.

Authors: D S Walton; R M Robb
Journal: Arch Ophthalmol Date: 1970-11

8. Maternal folate deficiency and pregnancy wastage. IV. Effects of folic acid supplements, anticonvulsants, and oral contraceptives.

Authors: J A Pritchard; D E Scott; P J Whalley
Journal: Am J Obstet Gynecol Date: 1971-02-01 Impact factor: 8.661

9. Placental transfer and neonatal elimination of diphenylhydantoin.

Authors: B L Mirkin
Journal: Am J Obstet Gynecol Date: 1971-03-15 Impact factor: 8.661

10. Optic nerve hypoplasia with good visual acuity and visual field defects: a study of children of diabetic mothers.

Authors: R A Petersen; D S Walton
Journal: Arch Ophthalmol Date: 1977-02

9 in total

Review 1. Prenatal determinants of optic nerve hypoplasia: review of suggested correlates and future focus.

Authors: Pamela Garcia-Filion; Mark Borchert
Journal: Surv Ophthalmol Date: 2013 Nov-Dec Impact factor: 6.048

2. Localising patterns of optic nerve hypoplasia--retina to occipital lobe.

Authors: P Novakovic; D S Taylor; W F Hoyt
Journal: Br J Ophthalmol Date: 1988-03 Impact factor: 4.638

Review 3. Optic nerve hypoplasia in children.

Authors: S M Zeki; G N Dutton
Journal: Br J Ophthalmol Date: 1990-05 Impact factor: 4.638