Literature DB >> 11588249

Global efforts in structural genomics.

R C Stevens1, S Yokoyama, I A Wilson.   

Abstract

A worldwide initiative in structural genomics aims to capitalize on the recent successes of the genome projects. Substantial new investments in structural genomics in the past 2 years indicate the high level of support for these international efforts. Already, enormous progress has been made on high-throughput methodologies and technologies that will speed up macromolecular structure determinations. Recent international meetings have resulted in the formation of an International Structural Genomics Organization to formulate policy and foster cooperation between the public and private efforts.

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Year:  2001        PMID: 11588249     DOI: 10.1126/science.1066011

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  52 in total

1.  NMR-based structural characterization of large protein-ligand interactions.

Authors:  Maurizio Pellecchia; David Meininger; Qing Dong; Edcon Chang; Rick Jack; Daniel S Sem
Journal:  J Biomol NMR       Date:  2002-02       Impact factor: 2.835

2.  A global representation of the protein fold space.

Authors:  Jingtong Hou; Gregory E Sims; Chao Zhang; Sung-Hou Kim
Journal:  Proc Natl Acad Sci U S A       Date:  2003-02-26       Impact factor: 11.205

3.  Autotracing of Escherichia coli acetate CoA-transferase alpha-subunit structure using 3.4 A MAD and 1.9 A native data.

Authors:  S Korolev; O Koroleva; K Petterson; M Gu; F Collart; I Dementieva; A Joachimiak
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2002-11-23

Review 4.  Protein crystallization for genomics: throughput versus output.

Authors:  Naomi E Chayen
Journal:  J Struct Funct Genomics       Date:  2003

5.  Secure web book to store structural genomics research data.

Authors:  Babu A Manjasetty; Klaus Höppner; Uwe Mueller; Udo Heinemann
Journal:  J Struct Funct Genomics       Date:  2003

6.  Rapid refinement of crystallographic protein construct definition employing enhanced hydrogen/deuterium exchange MS.

Authors:  Dennis Pantazatos; Jack S Kim; Heath E Klock; Raymond C Stevens; Ian A Wilson; Scott A Lesley; Virgil L Woods
Journal:  Proc Natl Acad Sci U S A       Date:  2004-01-08       Impact factor: 11.205

7.  On the evaluation and optimization of protein X-ray structures for pKa calculations.

Authors:  Jens Erik Nielsen; J Andrew McCammon
Journal:  Protein Sci       Date:  2003-02       Impact factor: 6.725

8.  Improving baculovirus recombination.

Authors:  Yuguang Zhao; David A G Chapman; Ian M Jones
Journal:  Nucleic Acids Res       Date:  2003-01-15       Impact factor: 16.971

9.  Role for NMR in structural genomics.

Authors:  Michael A Kennedy; Gaetano T Montelione; Cheryl H Arrowsmith; John L Markley
Journal:  J Struct Funct Genomics       Date:  2002

10.  Rapid purification and crystal structure analysis of a small protein carrying two terminal affinity tags.

Authors:  Uwe Mueller; Konrad Büssow; Anne Diehl; Franz J Bartl; Frank H Niesen; Lajos Nyarsik; Udo Heinemann
Journal:  J Struct Funct Genomics       Date:  2003
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