Literature DB >> 11583612

Common themes in mechanisms of gene silencing.

D Moazed1.   

Abstract

The assembly of DNA into regions of inaccessible chromatin, called silent chromatin, is involved in the regulation of gene expression and maintenance of chromosome stability in eukaryotes. Recent studies on Sir2-containing silencing complexes in budding yeast and HP1- and Swi6-containing silencing complexes in metazoans and fission yeast suggest a common mechanism for the assembly of these domains, which involves the physical coupling of histone modifying enzymes to histone binding proteins.

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Year:  2001        PMID: 11583612     DOI: 10.1016/s1097-2765(01)00340-9

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  108 in total

1.  A molecular link between gene-specific and chromosome-wide transcriptional repression.

Authors:  Diana S Chu; Heather E Dawes; Jason D Lieb; Raymond C Chan; Annie F Kuo; Barbara J Meyer
Journal:  Genes Dev       Date:  2002-04-01       Impact factor: 11.361

2.  Rap1p and other transcriptional regulators can function in defining distinct domains of gene expression.

Authors:  Qun Yu; Runxiang Qiu; Travis B Foland; Dan Griesen; Carl S Galloway; Ya-Hui Chiu; Joseph Sandmeier; James R Broach; Xin Bi
Journal:  Nucleic Acids Res       Date:  2003-02-15       Impact factor: 16.971

3.  Mouse chromocenters contain associated telomeric DNA and telomerase activity.

Authors:  P V Dmitriev; A N Prusov; A V Petrov; O A Dontsova; O V Zatsepina; A A Bogdanov
Journal:  Dokl Biol Sci       Date:  2002 Mar-Apr

4.  Ordered nucleation and spreading of silenced chromatin in Saccharomyces cerevisiae.

Authors:  Laura N Rusché; Ann L Kirchmaier; Jasper Rine
Journal:  Mol Biol Cell       Date:  2002-07       Impact factor: 4.138

Review 5.  Gene silencing-based disease resistance.

Authors:  Michael Wassenegger
Journal:  Transgenic Res       Date:  2002-12       Impact factor: 2.788

6.  Direct interaction with a nuclear protein and regulation of gene silencing by a variant of the Ca2+-channel beta 4 subunit.

Authors:  H Hibino; R Pironkova; O Onwumere; M Rousset; P Charnet; A J Hudspeth; F Lesage
Journal:  Proc Natl Acad Sci U S A       Date:  2002-12-23       Impact factor: 11.205

7.  A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse beta-globin locus.

Authors:  Michael Bulger; Dirk Schübeler; M A Bender; Joan Hamilton; Catherine M Farrell; Ross C Hardison; Mark Groudine
Journal:  Mol Cell Biol       Date:  2003-08       Impact factor: 4.272

8.  The Swi/Snf chromatin remodeling complex is required for ribosomal DNA and telomeric silencing in Saccharomyces cerevisiae.

Authors:  Vardit Dror; Fred Winston
Journal:  Mol Cell Biol       Date:  2004-09       Impact factor: 4.272

Review 9.  Regulation of NAD+ metabolism, signaling and compartmentalization in the yeast Saccharomyces cerevisiae.

Authors:  Michiko Kato; Su-Ju Lin
Journal:  DNA Repair (Amst)       Date:  2014-08-02

10.  The budding yeast silencing protein Sir1 is a functional component of centromeric chromatin.

Authors:  Judith A Sharp; Denise C Krawitz; Kelly A Gardner; Catherine A Fox; Paul D Kaufman
Journal:  Genes Dev       Date:  2003-09-15       Impact factor: 11.361

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