Literature DB >> 15340082

The Swi/Snf chromatin remodeling complex is required for ribosomal DNA and telomeric silencing in Saccharomyces cerevisiae.

Vardit Dror1, Fred Winston.   

Abstract

The Swi/Snf chromatin remodeling complex has been previously demonstrated to be required for transcriptional activation and repression of a subset of genes in Saccharomyces cerevisiae. In this work we demonstrate that Swi/Snf is also required for repression of RNA polymerase II-dependent transcription in the ribosomal DNA (rDNA) locus (rDNA silencing). This repression appears to be independent of both Sir2 and Set1, two factors known to be required for rDNA silencing. In contrast to many other rDNA silencing mutants that have elevated levels of rDNA recombination, snf2Delta mutants have a significantly decreased level of rDNA recombination. Additional studies have demonstrated that Swi/Snf is also required for silencing of genes near telomeres while having no detectable effect on silencing of HML or HMR.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15340082      PMCID： PMC515061          DOI： 10.1128/MCB.24.18.8227-8235.2004

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  69 in total

1.  The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases.

Authors:  J Landry; A Sutton; S T Tafrov; R C Heller; J Stebbins; L Pillus; R Sternglanz
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-23       Impact factor: 11.205

2.  Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription.

Authors:  P Komarnitsky; E J Cho; S Buratowski
Journal:  Genes Dev       Date:  2000-10-01       Impact factor: 11.361

3.  Transcription in the yeast rRNA gene locus: distribution of the active gene copies and chromatin structure of their flanking regulatory sequences.

Authors:  R Dammann; R Lucchini; T Koller; J M Sogo
Journal:  Mol Cell Biol       Date:  1995-10       Impact factor: 4.272

4.  Chromatin structure snap-shots: rapid nuclease digestion of chromatin in yeast.

Authors:  N A Kent; J Mellor
Journal:  Nucleic Acids Res       Date:  1995-09-25       Impact factor: 16.971

5.  DNA-binding properties of the yeast SWI/SNF complex.

Authors:  J Quinn; A M Fyrberg; R W Ganster; M C Schmidt; C L Peterson
Journal:  Nature       Date:  1996-02-29       Impact factor: 49.962

6.  Essential roles of Snf5p in Snf-Swi chromatin remodeling in vivo.

Authors:  F Geng; Y Cao; B C Laurent
Journal:  Mol Cell Biol       Date:  2001-07       Impact factor: 4.272

7.  The S. cerevisiae SAGA complex functions in vivo as a coactivator for transcriptional activation by Gal4.

Authors:  E Larschan; F Winston
Journal:  Genes Dev       Date:  2001-08-01       Impact factor: 11.361

8.  A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

Authors:  J S Smith; C B Brachmann; I Celic; M A Kenna; S Muhammad; V J Starai; J L Avalos; J C Escalante-Semerena; C Grubmeyer; C Wolberger; J D Boeke
Journal:  Proc Natl Acad Sci U S A       Date:  2000-06-06       Impact factor: 11.205

9.  Construction of a set of convenient Saccharomyces cerevisiae strains that are isogenic to S288C.

Authors:  F Winston; C Dollard; S L Ricupero-Hovasse
Journal:  Yeast       Date:  1995-01       Impact factor: 3.239

10.  Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex.

Authors:  J Côté; J Quinn; J L Workman; C L Peterson
Journal:  Science       Date:  1994-07-01       Impact factor: 47.728
View more
  33 in total

Review 1.  Linking DNA replication to heterochromatin silencing and epigenetic inheritance.

Authors:  Qing Li; Zhiguo Zhang
Journal:  Acta Biochim Biophys Sin (Shanghai)       Date:  2012-01       Impact factor: 3.848

2.  Distinct subregions of Swi1 manifest striking differences in prion transmission and SWI/SNF function.

Authors:  Zhiqiang Du; Emily T Crow; Hyun Seok Kang; Liming Li
Journal:  Mol Cell Biol       Date:  2010-08-02       Impact factor: 4.272

3.  Sir2 represses endogenous polymerase II transcription units in the ribosomal DNA nontranscribed spacer.

Authors:  Chonghua Li; John E Mueller; Mary Bryk
Journal:  Mol Biol Cell       Date:  2006-06-28       Impact factor: 4.138

Review 4.  Mechanisms of ATP dependent chromatin remodeling.

Authors:  Vamsi K Gangaraju; Blaine Bartholomew
Journal:  Mutat Res       Date:  2007-01-21       Impact factor: 2.433

5.  Distinct roles for the essential MYST family HAT Esa1p in transcriptional silencing.

Authors:  Astrid S Clarke; Eva Samal; Lorraine Pillus
Journal:  Mol Biol Cell       Date:  2006-01-25       Impact factor: 4.138

6.  Limiting the extent of the RDN1 heterochromatin domain by a silencing barrier and Sir2 protein levels in Saccharomyces cerevisiae.

Authors:  Moumita Biswas; Nazif Maqani; Ragini Rai; Srikala P Kumaran; Kavitha R Iyer; Erdem Sendinc; Jeffrey S Smith; Shikha Laloraya
Journal:  Mol Cell Biol       Date:  2009-03-16       Impact factor: 4.272

7.  Isw1 acts independently of the Isw1a and Isw1b complexes in regulating transcriptional silencing at the ribosomal DNA locus in Saccharomyces cerevisiae.

Authors:  John E Mueller; Mary Bryk
Journal:  J Mol Biol       Date:  2007-05-18       Impact factor: 5.469

8.  Roles of chromatin remodeling factors in the formation and maintenance of heterochromatin structure.

Authors:  Qun Yu; Xinmin Zhang; Xin Bi
Journal:  J Biol Chem       Date:  2011-03-09       Impact factor: 5.157

9.  Distinct roles of non-canonical poly(A) polymerases in RNA metabolism.

Authors:  Salvatore San Paolo; Stepanka Vanacova; Luca Schenk; Tanja Scherrer; Diana Blank; Walter Keller; André P Gerber
Journal:  PLoS Genet       Date:  2009-07-10       Impact factor: 5.917

10.  The SNF2-family member Fun30 promotes gene silencing in heterochromatic loci.

Authors:  Ana Neves-Costa; W Ryan Will; Anna T Vetter; J Ross Miller; Patrick Varga-Weisz
Journal:  PLoS One       Date:  2009-12-01       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.