R E Andersson1. 1. Department of Surgery, Ryhov Hospital, S-551 85, Jönköping, Sweden. roland.andersson@ryhov.ltjkpg.se
Abstract
BACKGROUND: This study analysed the risk of surgically treated small bowel obstruction after open appendicectomy. METHODS: This was a historical cohort study of 245 400 patients who underwent open appendicectomy and population-based matched controls, identified by linkage of computer registries. Analyses were made with the life-table technique, Kaplan-Meier plots and Cox proportional hazards regression analysis. RESULTS: The cumulated risk of surgically treated small bowel obstruction after appendicectomy was 0.41 per cent after 4 weeks, 0.63 per cent after 1 year and 1.30 per cent after 30 years of follow-up, compared with 0.003 per cent at 1 year and 0.21 per cent after 30 years of follow-up among the non-operated controls. The highest risk was found after operation for other diagnoses (adjusted hazard ratio 5.2 (95 per cent confidence interval 4.6-5.8)), followed by operation for perforated appendicitis (adjusted hazard ratio 3.5 (3.1-3.8)), non-specific abdominal pain (adjusted hazard ratio 2.6 (2.3-3.0)) and mesenteric lymphadenitis (adjusted hazard ratio 2.4 (2.0-2.8)) compared with operation for non-perforated appendicitis. The relation with age was J shaped, with the lowest risk at 20-39 years. Women had a slightly lower risk than men. CONCLUSION: The risk of postoperative small bowel obstruction needing surgical treatment after open appendicectomy is lower than previously thought. Perforated appendicitis, negative appendicectomy and high age are the risk factors.
BACKGROUND: This study analysed the risk of surgically treated small bowel obstruction after open appendicectomy. METHODS: This was a historical cohort study of 245 400 patients who underwent open appendicectomy and population-based matched controls, identified by linkage of computer registries. Analyses were made with the life-table technique, Kaplan-Meier plots and Cox proportional hazards regression analysis. RESULTS: The cumulated risk of surgically treated small bowel obstruction after appendicectomy was 0.41 per cent after 4 weeks, 0.63 per cent after 1 year and 1.30 per cent after 30 years of follow-up, compared with 0.003 per cent at 1 year and 0.21 per cent after 30 years of follow-up among the non-operated controls. The highest risk was found after operation for other diagnoses (adjusted hazard ratio 5.2 (95 per cent confidence interval 4.6-5.8)), followed by operation for perforated appendicitis (adjusted hazard ratio 3.5 (3.1-3.8)), non-specific abdominal pain (adjusted hazard ratio 2.6 (2.3-3.0)) and mesenteric lymphadenitis (adjusted hazard ratio 2.4 (2.0-2.8)) compared with operation for non-perforated appendicitis. The relation with age was J shaped, with the lowest risk at 20-39 years. Women had a slightly lower risk than men. CONCLUSION: The risk of postoperative small bowel obstruction needing surgical treatment after open appendicectomy is lower than previously thought. Perforated appendicitis, negative appendicectomy and high age are the risk factors.
Authors: Sheraz R Markar; Simon Blackburn; Richard Cobb; Alan Karthikesalingam; Jessica Evans; James Kinross; Omar Faiz Journal: J Gastrointest Surg Date: 2012-07-19 Impact factor: 3.452
Authors: Jenneke T H Hamminga; H Sijbrand Hofker; Paul M A Broens; Philip M Kluin; Erik Heineman; Jan Willem Haveman Journal: Surg Endosc Date: 2012-10-17 Impact factor: 4.584