| Literature DB >> 11574622 |
M I Gómara1, D Cubitt, U Desselberger, J Gray.
Abstract
Rotavirus strains collected in the United Kingdom during the 1995-1996 season and genotyped as G2 by reverse transcription-PCR failed to serotype in enzyme-linked immunosorbent assays using three different G2-specific monoclonal antibodies. The deduced amino acid sequences of the antigenic regions A (amino acids 87 to 101), B (amino acids 142 to 152), and C (amino acids 208 to 221) of VP7 revealed that a substitution at position 96 (Asp-->Asn) correlated with the change in ability to serotype these G2 strains.Entities:
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Year: 2001 PMID: 11574622 PMCID: PMC88438 DOI: 10.1128/JCM.39.10.3796-3798.2001
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948