Literature DB >> 11540922

Chemical synthesis of oligoribonucleotides containing 2-aminopurine: substrates for the investigation of ribozyme function.

J A Doudna1, J W Szostak, A Rich, N Usman.   

Abstract

The chemical synthesis of a fully protected ribonucleoside phosphoramidite, containing 2-aminopurine as the base component, and its incorporation into short oligoribonucleotides as substrates for an engineered ribozyme from Tetrahymena is described.

Entities:  

Keywords:  NASA Discipline Exobiology; Non-NASA Center

Mesh：

Substances：

Year:  1990        PMID： 11540922     DOI： 10.1021/jo00308a003

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  10 in total

1.  Template-directed primer extension catalyzed by the Tetrahymena ribozyme.

Authors:  D P Bartel; J A Doudna; N Usman; J W Szostak
Journal:  Mol Cell Biol       Date:  1991-06       Impact factor: 4.272

2.  Pyrrolo-C as a fluorescent probe for monitoring RNA secondary structure formation.

Authors:  Rebecca A Tinsley; Nils G Walter
Journal:  RNA       Date:  2006-01-23       Impact factor: 4.942

3.  Combined Approaches to Site-Specific Modification of RNA.

Authors:  Christine S Chow; Santosh K Mahto; Tek N Lamichhane
Journal:  ACS Chem Biol       Date:  2008-01-05       Impact factor: 5.100

4.  Role of adenine functional groups in the recognition of the 3'-splice-site AG during the second step of pre-mRNA splicing.

Authors:  R K Gaur; L Beigelman; P Haeberli; T Maniatis
Journal:  Proc Natl Acad Sci U S A       Date:  2000-01-04       Impact factor: 11.205

5.  Total chemical synthesis of a ribozyme derived from a group I intron.

Authors:  S K Whoriskey; N Usman; J W Szostak
Journal:  Proc Natl Acad Sci U S A       Date:  1995-03-28       Impact factor: 11.205

6.  4-Cyanoindole-2'-deoxyribonucleoside (4CIN): A Universal Fluorescent Nucleoside Analogue.

Authors:  Kellan T Passow; Daniel A Harki
Journal:  Org Lett       Date:  2018-07-10       Impact factor: 6.005

7.  Synthesis of RNA containing inosine: analysis of the sequence requirements for the 5' splice site of the Tetrahymena group I intron.

Authors:  R Green; J W Szostak; S A Benner; A Rich; N Usman
Journal:  Nucleic Acids Res       Date:  1991-08-11       Impact factor: 16.971

8.  Base and sugar requirements for RNA cleavage of essential nucleoside residues in internal loop B of the hairpin ribozyme: implications for secondary structure.

Authors:  S Schmidt; L Beigelman; A Karpeisky; N Usman; U S Sorensen; M J Gait
Journal:  Nucleic Acids Res       Date:  1996-02-15       Impact factor: 16.971

9.  Synthesis and hydrolysis of oligodeoxyribonucleotides containing 2-aminopurine.

Authors:  J Fujimoto; Z Nuesca; M Mazurek; L C Sowers
Journal:  Nucleic Acids Res       Date:  1996-02-15       Impact factor: 16.971

10.  T box transcription antitermination riboswitch: influence of nucleotide sequence and orientation on tRNA binding by the antiterminator element.

Authors:  Hamid Fauzi; Akwasi Agyeman; Jennifer V Hines
Journal:  Biochim Biophys Acta       Date:  2008-12-25
  10 in total

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