Literature DB >> 11539196

A highly efficient 24-condition matrix for the crystallization of nucleic acid fragments.

I Berger1, C H Kang, N Sinha, M Wolters, A Rich.   

Abstract

A matrix screen is presented with optimized conditions for the crystallization of nucleic acid fragments. The screen consists of 24 conditions only and utilizes minimal amounts of sample. It has been tested on a series of DNA and RNA oligomers, and yielded diffraction-quality crystals of many specimens including drug-DNA complexes. Preliminary X-ray analysis of the crystals is reported.

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Year:  1996        PMID： 11539196     DOI： 10.1107/s0907444995013564

Source DB:  PubMed          Journal:  Acta Crystallogr D Biol Crystallogr        ISSN： 0907-4449


  31 in total

1.  Crystal structure of acceptor stem of tRNA(Ala) from Escherichia coli shows unique G.U wobble base pair at 1.16 A resolution.

Authors:  U Mueller; H Schübel; M Sprinzl; U Heinemann
Journal:  RNA       Date:  1999-05       Impact factor: 4.942

2.  Crystal structure of d(GCGAAAGCT) containing a parallel-stranded duplex with homo base pairs and an anti-parallel duplex with Watson-Crick base pairs.

Authors:  Tomoko Sunami; Jiro Kondo; Tomonori Kobuna; Ichiro Hirao; Kimitsuna Watanabe; Kin-ichiro Miura; Akio Takénaka
Journal:  Nucleic Acids Res       Date:  2002-12-01       Impact factor: 16.971

3.  Lessons from high-throughput protein crystallization screening: 10 years of practical experience.

Authors:  Joseph R Luft; Edward H Snell; George T Detitta
Journal:  Expert Opin Drug Discov       Date:  2011-03-22       Impact factor: 6.098

4.  Crystallization and preliminary X-ray analysis of Escherichia coli RNase HI-dsRNA complexes.

Authors:  Lioudmila V Loukachevitch; Martin Egli
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2007-01-17

5.  Direct observation of two cyclohexenyl (CeNA) ring conformations in duplex DNA.

Authors:  Koen Robeyns; Piet Herdewijn; Luc Van Meervelt
Journal:  Artif DNA PNA XNA       Date:  2010-07

Review 6.  Diffraction Techniques in Structural Biology.

Authors:  Martin Egli
Journal:  Curr Protoc Nucleic Acid Chem       Date:  2016-06-01

7.  Crystallization and preliminary X-ray study of the D-altritol oligonucleotide GTGTACAC.

Authors:  Margriet Ovaere; Arthur Van Aerschot; Mikhail Abramov; Piet Herdewijn; Luc Van Meervelt
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2010-03-31

8.  Structural origins of the exonuclease resistance of a zwitterionic RNA.

Authors:  M Teplova; S T Wallace; V Tereshko; G Minasov; A M Symons; P D Cook; M Manoharan; M Egli
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-07       Impact factor: 11.205

9.  2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.

Authors:  Feng Li; Sanjay Sarkhel; Christopher J Wilds; Zdzislaw Wawrzak; Thazha P Prakash; Muthiah Manoharan; Martin Egli
Journal:  Biochemistry       Date:  2006-04-04       Impact factor: 3.162

10.  A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' cross-links by nitrogen mustards.

Authors:  Feng Wang; Feng Li; Manjori Ganguly; Luis A Marky; Barry Gold; Martin Egli; Michael P Stone
Journal:  Biochemistry       Date:  2008-06-13       Impact factor: 3.162
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