Literature DB >> 11536525

Liquid water and the origin of life.

A Brack1.   

Abstract

Liquid water has many peculiarities which confer special properties. The most important among them probably are the ability to establish hydrogen bonds, a high polarity and a high dielectric constant. In the presence of liquid water, large organic molecules have to manage the conflict between hydrophobic groups and hydrophilic groups. This duality can generate interesting prebiotic situations such as the stereoselective aggregation of short peptide sequences of alternating hydrophobic-hydrophilic residues into thermostable beta-sheets endowed with chemical activity. Liquid water is also a powerful hydrolytic agent. As such, it allows pathways which would have few chances to occur in an organic solvent.

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Year:  1993        PMID: 11536525     DOI: 10.1007/bf01581985

Source DB:  PubMed          Journal:  Orig Life Evol Biosph        ISSN: 0169-6149            Impact factor:   1.950


  12 in total

1.  Beta structures of alternating polypeptides and their possible prebiotic significance.

Authors:  A Brack; L E Orgel
Journal:  Nature       Date:  1975-07-31       Impact factor: 49.962

2.  N,N'-carbonyldiimidazole-induced peptide formation in aqueous solution.

Authors:  K W Ehler; L E Orgel
Journal:  Biochim Biophys Acta       Date:  1976-05-20

3.  Selective emergence and survival of early polypeptides in water.

Authors:  A Brack
Journal:  Orig Life Evol Biosph       Date:  1987       Impact factor: 1.950

4.  Beta-structures of polypeptides with L-and D-residues. Part II. Statistical analysis and enrichment in enantiomer.

Authors:  G Spach; A Brack
Journal:  J Mol Evol       Date:  1979-06-08       Impact factor: 2.395

5.  Aminoacyle transfer: peptide synthesis and other properties of an amino acid imidazolide.

Authors:  A L Weber; J C Lacey
Journal:  Biochim Biophys Acta       Date:  1974-05-17

6.  Enantiomer enrichment in early peptides.

Authors:  A Brack; G Spach
Journal:  Orig Life       Date:  1981 Mar-Jun

7.  Chemical activity of simple basic peptides.

Authors:  A Brack; B Barbier
Journal:  Orig Life Evol Biosph       Date:  1990       Impact factor: 1.950

8.  The general synthetic route to amino acid esters of nucleotides and nucleoside-5'-triphosphates and some properties of these compounds.

Authors:  B P Gottikh; A A Krayevsky; N B Tarussova; P P Purygin; T L Tsilevich
Journal:  Tetrahedron       Date:  1970-09       Impact factor: 2.457

9.  Experiments on the abiotic amplification of optical activity.

Authors:  W A Bonner; N E Blair; F M Dirbas
Journal:  Orig Life       Date:  1981 Mar-Jun

10.  Aqueous polymerization of L-amino acid active esters in bicarbonate solution via Leuchs' anhydrides.

Authors:  A Brack
Journal:  Biosystems       Date:  1982       Impact factor: 1.973

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  6 in total

Review 1.  Habitable zones around low mass stars and the search for extraterrestrial life.

Authors:  J F Kasting
Journal:  Orig Life Evol Biosph       Date:  1997-06       Impact factor: 1.950

2.  Theory of the origin, evolution, and nature of life.

Authors:  Erik D Andrulis
Journal:  Life (Basel)       Date:  2011-12-23

Review 3.  Speculations on the origin of the genetic code.

Authors:  H Hartman
Journal:  J Mol Evol       Date:  1995-05       Impact factor: 2.395

4.  Desulfotomaculum and Methanobacterium spp. dominate a 4- to 5-kilometer-deep fault.

Authors:  Duane P Moser; Thomas M Gihring; Fred J Brockman; James K Fredrickson; David L Balkwill; Michael E Dollhopf; Barbara Sherwood Lollar; Lisa M Pratt; Erik Boice; Gordon Southam; Greg Wanger; Brett J Baker; Susan M Pfiffner; Li-Hung Lin; T C Onstott
Journal:  Appl Environ Microbiol       Date:  2005-12       Impact factor: 4.792

5.  Water and Life: The Medium is the Message.

Authors:  Moran Frenkel-Pinter; Vahab Rajaei; Jennifer B Glass; Nicholas V Hud; Loren Dean Williams
Journal:  J Mol Evol       Date:  2021-01-11       Impact factor: 2.395

6.  A Statistical Approach to Illustrate the Challenge of Astrobiology for Public Outreach.

Authors:  Frédéric Foucher; Keyron Hickman-Lewis; Frances Westall; André Brack
Journal:  Life (Basel)       Date:  2017-10-26
  6 in total

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